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http://purl.uniprot.org/citations/1662763http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1662763http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1662763http://www.w3.org/2000/01/rdf-schema#comment"Evidence for pleiotropic activation of virulence genes in Listeria monocytogenes is presented. A complementation study of a spontaneous prfA-deletion mutant and analysis of cassette and transposon insertion mutants showed that the gene prfA activates the transcription of four independent genes which code for a phosphatidyl-inositol-specific phospholipase C (gene plcA), listeriolysin O (gene hlyA), a metallo-protease (gene prtA) and a lecithinase (gene prtC). Transcription of prfA is not constitutive. During the growth phase, two peaks of prfA transcript accumulation were observed: the first was during exponential growth, and the second was at the beginning of the stationary phase. In addition, two prfA-specific transcripts of 2.2 kb and 1 kb are detected. Early in exponential growth, prfA is co-transcribed with plcA which lies upstream prfA, giving rise to the 2.2 kb plcA-prfA transcript. In late-exponential growth and at the beginning of the stationary phase, prfA transcripts of 1 kb are predominantly detected. Our results demonstrate that since prfA controls plcA transcription, it also regulates its own synthesis."xsd:string
http://purl.uniprot.org/citations/1662763http://purl.org/dc/terms/identifier"doi:10.1111/j.1365-2958.1991.tb02158.x"xsd:string
http://purl.uniprot.org/citations/1662763http://purl.org/dc/terms/identifier"doi:10.1111/j.1365-2958.1991.tb02158.x"xsd:string
http://purl.uniprot.org/citations/1662763http://purl.uniprot.org/core/author"Cossart P."xsd:string
http://purl.uniprot.org/citations/1662763http://purl.uniprot.org/core/author"Cossart P."xsd:string
http://purl.uniprot.org/citations/1662763http://purl.uniprot.org/core/author"Dramsi S."xsd:string
http://purl.uniprot.org/citations/1662763http://purl.uniprot.org/core/author"Dramsi S."xsd:string
http://purl.uniprot.org/citations/1662763http://purl.uniprot.org/core/author"Gouin E."xsd:string
http://purl.uniprot.org/citations/1662763http://purl.uniprot.org/core/author"Gouin E."xsd:string
http://purl.uniprot.org/citations/1662763http://purl.uniprot.org/core/author"Mengaud J."xsd:string
http://purl.uniprot.org/citations/1662763http://purl.uniprot.org/core/author"Mengaud J."xsd:string
http://purl.uniprot.org/citations/1662763http://purl.uniprot.org/core/author"Milon G."xsd:string
http://purl.uniprot.org/citations/1662763http://purl.uniprot.org/core/author"Milon G."xsd:string
http://purl.uniprot.org/citations/1662763http://purl.uniprot.org/core/author"Vazquez-Boland J.A."xsd:string
http://purl.uniprot.org/citations/1662763http://purl.uniprot.org/core/author"Vazquez-Boland J.A."xsd:string
http://purl.uniprot.org/citations/1662763http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/1662763http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/1662763http://purl.uniprot.org/core/name"Mol. Microbiol."xsd:string
http://purl.uniprot.org/citations/1662763http://purl.uniprot.org/core/name"Mol. Microbiol."xsd:string
http://purl.uniprot.org/citations/1662763http://purl.uniprot.org/core/pages"2273-2283"xsd:string
http://purl.uniprot.org/citations/1662763http://purl.uniprot.org/core/pages"2273-2283"xsd:string
http://purl.uniprot.org/citations/1662763http://purl.uniprot.org/core/title"Pleiotropic control of Listeria monocytogenes virulence factors by a gene that is autoregulated."xsd:string
http://purl.uniprot.org/citations/1662763http://purl.uniprot.org/core/title"Pleiotropic control of Listeria monocytogenes virulence factors by a gene that is autoregulated."xsd:string