RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/16648605http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16648605http://www.w3.org/2000/01/rdf-schema#comment"The single nucleotide polymorphism at position 276 in the adiponectin gene (APM1/ACDC +276 G>T) and left ventricular mass (LVM) have been associated with increased cardiovascular risk. We sought to evaluate whether +276 G>T variants in the adiponectin gene are correlated with LVM in uncomplicated obese subjects. APM1/ACDC +276 G>T single nucleotide polymorphism, echocardiographic indexed LVM (LVM/body surface area and LVM/height(2.7)), insulin sensitivity by euglycemic clamp, and plasma adiponectin levels were analyzed in 62 obese subjects without complications (51 women and 11 men; mean age, 34.2 +/- 10.2 years; BMI, 38.6 +/-9.1 kg/m2). Forty lean subjects formed the control group for LVM evaluation. We found 23 (37%) uncomplicated obese subjects with the APM1/ACDC +276 G/G genotype, 25 (40%) with the G/T genotype, and 14 (23%) with the T/T genotype. G/G uncomplicated obese subjects showed significant higher LVM/body surface area and LVM/height(2.7) (within the normal range in the majority of them) than uncomplicated obese subjects carrying the G/T and T/T genotypes (p < 0.01 and p < 0.05, respectively). This study showed that LVM is significantly higher in uncomplicated obese subjects carrying the G/G genotype at position 276 of the human adiponectin gene."xsd:string
http://purl.uniprot.org/citations/16648605http://purl.org/dc/terms/identifier"doi:10.1038/oby.2006.48"xsd:string
http://purl.uniprot.org/citations/16648605http://purl.uniprot.org/core/author"Buzzetti R."xsd:string
http://purl.uniprot.org/citations/16648605http://purl.uniprot.org/core/author"Petrone A."xsd:string
http://purl.uniprot.org/citations/16648605http://purl.uniprot.org/core/author"Leonetti F."xsd:string
http://purl.uniprot.org/citations/16648605http://purl.uniprot.org/core/author"Iacobellis G."xsd:string
http://purl.uniprot.org/citations/16648605http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16648605http://purl.uniprot.org/core/name"Obesity (Silver Spring)"xsd:string
http://purl.uniprot.org/citations/16648605http://purl.uniprot.org/core/pages"368-372"xsd:string
http://purl.uniprot.org/citations/16648605http://purl.uniprot.org/core/title"Left ventricular mass and +276 G/G single nucleotide polymorphism of the adiponectin gene in uncomplicated obesity."xsd:string
http://purl.uniprot.org/citations/16648605http://purl.uniprot.org/core/volume"14"xsd:string
http://purl.uniprot.org/citations/16648605http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16648605
http://purl.uniprot.org/citations/16648605http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/16648605
http://purl.uniprot.org/uniprot/#_A8K660-mappedCitation-16648605http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16648605
http://purl.uniprot.org/uniprot/#_B2R773-mappedCitation-16648605http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16648605
http://purl.uniprot.org/uniprot/#_Q15848-mappedCitation-16648605http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16648605
http://purl.uniprot.org/uniprot/B2R773http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/16648605
http://purl.uniprot.org/uniprot/A8K660http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/16648605
http://purl.uniprot.org/uniprot/Q15848http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/16648605