http://purl.uniprot.org/citations/16648605 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16648605 | http://www.w3.org/2000/01/rdf-schema#comment | "The single nucleotide polymorphism at position 276 in the adiponectin gene (APM1/ACDC +276 G>T) and left ventricular mass (LVM) have been associated with increased cardiovascular risk. We sought to evaluate whether +276 G>T variants in the adiponectin gene are correlated with LVM in uncomplicated obese subjects. APM1/ACDC +276 G>T single nucleotide polymorphism, echocardiographic indexed LVM (LVM/body surface area and LVM/height(2.7)), insulin sensitivity by euglycemic clamp, and plasma adiponectin levels were analyzed in 62 obese subjects without complications (51 women and 11 men; mean age, 34.2 +/- 10.2 years; BMI, 38.6 +/-9.1 kg/m2). Forty lean subjects formed the control group for LVM evaluation. We found 23 (37%) uncomplicated obese subjects with the APM1/ACDC +276 G/G genotype, 25 (40%) with the G/T genotype, and 14 (23%) with the T/T genotype. G/G uncomplicated obese subjects showed significant higher LVM/body surface area and LVM/height(2.7) (within the normal range in the majority of them) than uncomplicated obese subjects carrying the G/T and T/T genotypes (p < 0.01 and p < 0.05, respectively). This study showed that LVM is significantly higher in uncomplicated obese subjects carrying the G/G genotype at position 276 of the human adiponectin gene."xsd:string |
http://purl.uniprot.org/citations/16648605 | http://purl.org/dc/terms/identifier | "doi:10.1038/oby.2006.48"xsd:string |
http://purl.uniprot.org/citations/16648605 | http://purl.uniprot.org/core/author | "Buzzetti R."xsd:string |
http://purl.uniprot.org/citations/16648605 | http://purl.uniprot.org/core/author | "Petrone A."xsd:string |
http://purl.uniprot.org/citations/16648605 | http://purl.uniprot.org/core/author | "Leonetti F."xsd:string |
http://purl.uniprot.org/citations/16648605 | http://purl.uniprot.org/core/author | "Iacobellis G."xsd:string |
http://purl.uniprot.org/citations/16648605 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
http://purl.uniprot.org/citations/16648605 | http://purl.uniprot.org/core/name | "Obesity (Silver Spring)"xsd:string |
http://purl.uniprot.org/citations/16648605 | http://purl.uniprot.org/core/pages | "368-372"xsd:string |
http://purl.uniprot.org/citations/16648605 | http://purl.uniprot.org/core/title | "Left ventricular mass and +276 G/G single nucleotide polymorphism of the adiponectin gene in uncomplicated obesity."xsd:string |
http://purl.uniprot.org/citations/16648605 | http://purl.uniprot.org/core/volume | "14"xsd:string |
http://purl.uniprot.org/citations/16648605 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16648605 |
http://purl.uniprot.org/citations/16648605 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16648605 |
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http://purl.uniprot.org/uniprot/A8K660 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/16648605 |
http://purl.uniprot.org/uniprot/Q15848 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/16648605 |