| http://purl.uniprot.org/citations/16671949 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16671949 | http://www.w3.org/2000/01/rdf-schema#comment | "It is well known that certain HLA class II alleles confer an increased risk for developing multiple sclerosis (MS). Recent studies have suggested HLA class I as a region that may also contribute to the development of MS. In this study, we investigated the association between HLA-DR, HLA-B alleles, and major histocompatibility complex (MHC) class I-chain-related gene A (MICA) transmembrane (MICA-TM) polymorphisms and disease progression in 104 MS patients and 116 healthy controls. DR1 was found to be decreased in patients when compared with controls (p(c) = 0.012). Neither HLA-B nor HLA-DR alleles were found to be associated with MS susceptibility. Furthermore, the prevalence of MICA-A5 in patients with relapsing MS was 9% while the prevalence in progressive forms was 42% (p(c) = 0.0015). The extended haplotypes related to MICA-TM5 that were found in our population were DR7-MICA5-B64 (EH 64.1, delta(s) = 0.38), DR4-MICA5-B62 (EH 62.1, delta(s) = 0.28), and DR11-MICA5-B35 (EH35.1, delta(s) = 0.10), but none of them were found to be associated to MS susceptibility or disease progression. Our data could indicate a possible role of MICA-TM in MS prognosis."xsd:string |
| http://purl.uniprot.org/citations/16671949 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1399-0039.2006.00593.x"xsd:string |
| http://purl.uniprot.org/citations/16671949 | http://purl.uniprot.org/core/author | "Gonzalez S."xsd:string |
| http://purl.uniprot.org/citations/16671949 | http://purl.uniprot.org/core/author | "Lopez-Larrea C."xsd:string |
| http://purl.uniprot.org/citations/16671949 | http://purl.uniprot.org/core/author | "Lopez-Vazquez A."xsd:string |
| http://purl.uniprot.org/citations/16671949 | http://purl.uniprot.org/core/author | "Martinez-Borra J."xsd:string |
| http://purl.uniprot.org/citations/16671949 | http://purl.uniprot.org/core/author | "Rodrigo L."xsd:string |
| http://purl.uniprot.org/citations/16671949 | http://purl.uniprot.org/core/author | "Rodriguez-Rodero S."xsd:string |
| http://purl.uniprot.org/citations/16671949 | http://purl.uniprot.org/core/author | "Lahoz C.H."xsd:string |
| http://purl.uniprot.org/citations/16671949 | http://purl.uniprot.org/core/author | "Fdez-Morera J.L."xsd:string |
| http://purl.uniprot.org/citations/16671949 | http://purl.uniprot.org/core/author | "Tunon A."xsd:string |
| http://purl.uniprot.org/citations/16671949 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16671949 | http://purl.uniprot.org/core/name | "Tissue Antigens"xsd:string |
| http://purl.uniprot.org/citations/16671949 | http://purl.uniprot.org/core/pages | "409-414"xsd:string |
| http://purl.uniprot.org/citations/16671949 | http://purl.uniprot.org/core/title | "Clinical behavior of multiple sclerosis is modulated by the MHC class I-chain-related gene A."xsd:string |
| http://purl.uniprot.org/citations/16671949 | http://purl.uniprot.org/core/volume | "67"xsd:string |
| http://purl.uniprot.org/citations/16671949 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16671949 |
| http://purl.uniprot.org/citations/16671949 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16671949 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-16671949 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16671949 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-16671949 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16671949 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I5-mappedCitation-16671949 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16671949 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C552-mappedCitation-16671949 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16671949 |
| http://purl.uniprot.org/uniprot/#_A0A0E3DC98-mappedCitation-16671949 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16671949 |
| http://purl.uniprot.org/uniprot/#_A0A0E3DCA0-mappedCitation-16671949 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16671949 |