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http://purl.uniprot.org/citations/16678167http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16678167http://www.w3.org/2000/01/rdf-schema#comment"HEN1-dependent methylation of the 3'-terminal nucleotide is a crucial step in plant microRNA (miRNA) biogenesis. Here we report that several viral RNA silencing suppressors (P1/HC-Pro, p21 and p19) inhibit miRNA methylation. These suppressors have distinct effects on different miRNAs. We also show that miRNA* is methylated in vivo in a suppressor-sensitive manner, suggesting that the viral proteins interfere with miRNA/miRNA* duplexes. p19 and p21 bind both methylated and unmethylated miRNA/miRNA* duplexes in vivo. These findings suggest miRNA/miRNA* as the in vivo substrates for the HEN1 miRNA methyltransferase and raise intriguing possibilities regarding the cellular location of miRNA methylation."xsd:string
http://purl.uniprot.org/citations/16678167http://purl.org/dc/terms/identifier"doi:10.1016/j.febslet.2006.04.063"xsd:string
http://purl.uniprot.org/citations/16678167http://purl.uniprot.org/core/author"Carrington J.C."xsd:string
http://purl.uniprot.org/citations/16678167http://purl.uniprot.org/core/author"Chen X."xsd:string
http://purl.uniprot.org/citations/16678167http://purl.uniprot.org/core/author"Yang Z."xsd:string
http://purl.uniprot.org/citations/16678167http://purl.uniprot.org/core/author"Yu B."xsd:string
http://purl.uniprot.org/citations/16678167http://purl.uniprot.org/core/author"Chapman E.J."xsd:string
http://purl.uniprot.org/citations/16678167http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16678167http://purl.uniprot.org/core/name"FEBS Lett"xsd:string
http://purl.uniprot.org/citations/16678167http://purl.uniprot.org/core/pages"3117-3120"xsd:string
http://purl.uniprot.org/citations/16678167http://purl.uniprot.org/core/title"Transgenically expressed viral RNA silencing suppressors interfere with microRNA methylation in Arabidopsis."xsd:string
http://purl.uniprot.org/citations/16678167http://purl.uniprot.org/core/volume"580"xsd:string
http://purl.uniprot.org/citations/16678167http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16678167
http://purl.uniprot.org/citations/16678167http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/16678167
http://purl.uniprot.org/uniprot/#_Q9C5Q8-mappedCitation-16678167http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16678167
http://purl.uniprot.org/uniprot/Q9C5Q8http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/16678167