| http://purl.uniprot.org/citations/16679311 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16679311 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16679311 | http://www.w3.org/2000/01/rdf-schema#comment | "Pex19p is required for the topogenesis of peroxisomal membrane proteins (PMPs). Here we have demonstrated that Pex19p is also required for the peroxisomal targeting and stability of Pex17p, a peripheral component of the docking complex of the peroxisomal protein import machinery. We have demonstrated that Pex17p is associated with the peroxisomal Pex13p-Pex14p complex as well as with Pex19p. We have identified the corresponding binding sites for Pex14p and Pex19p and demonstrated that a specific loss of the Pex19p interaction resulted in mistargeting of Pex17p. We have shown that a construct consisting only of the Pex19p- and Pex14p-binding sites of Pex17p is sufficient to direct an otherwise cytosolic reporter protein to the peroxisomal membrane in a Pex19p-dependent manner. Our data show that the function of Pex19p as chaperone or import receptor is not restricted to integral membrane proteins but may also include peripheral PMPs. As a consequence of our data, the previous definition of a targeting signal for PMPs (mPTS) as a Pex19p-binding motif in conjunction with a transmembrane segment should be extended to regions comprising a Pex19p-binding motif and a peroxisomal anchor sequence."xsd:string |
| http://purl.uniprot.org/citations/16679311 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m603344200"xsd:string |
| http://purl.uniprot.org/citations/16679311 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m603344200"xsd:string |
| http://purl.uniprot.org/citations/16679311 | http://purl.uniprot.org/core/author | "Erdmann R."xsd:string |
| http://purl.uniprot.org/citations/16679311 | http://purl.uniprot.org/core/author | "Erdmann R."xsd:string |
| http://purl.uniprot.org/citations/16679311 | http://purl.uniprot.org/core/author | "Girzalsky W."xsd:string |
| http://purl.uniprot.org/citations/16679311 | http://purl.uniprot.org/core/author | "Girzalsky W."xsd:string |
| http://purl.uniprot.org/citations/16679311 | http://purl.uniprot.org/core/author | "Kunau W.-H."xsd:string |
| http://purl.uniprot.org/citations/16679311 | http://purl.uniprot.org/core/author | "Kunau W.-H."xsd:string |
| http://purl.uniprot.org/citations/16679311 | http://purl.uniprot.org/core/author | "Schemenewitz A."xsd:string |
| http://purl.uniprot.org/citations/16679311 | http://purl.uniprot.org/core/author | "Schemenewitz A."xsd:string |
| http://purl.uniprot.org/citations/16679311 | http://purl.uniprot.org/core/author | "Hoffmann L.S."xsd:string |
| http://purl.uniprot.org/citations/16679311 | http://purl.uniprot.org/core/author | "Hoffmann L.S."xsd:string |
| http://purl.uniprot.org/citations/16679311 | http://purl.uniprot.org/core/author | "Nolte A."xsd:string |
| http://purl.uniprot.org/citations/16679311 | http://purl.uniprot.org/core/author | "Nolte A."xsd:string |
| http://purl.uniprot.org/citations/16679311 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16679311 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16679311 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/16679311 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/16679311 | http://purl.uniprot.org/core/pages | "19417-19425"xsd:string |
| http://purl.uniprot.org/citations/16679311 | http://purl.uniprot.org/core/pages | "19417-19425"xsd:string |
| http://purl.uniprot.org/citations/16679311 | http://purl.uniprot.org/core/title | "Pex19p-dependent targeting of Pex17p, a peripheral component of the peroxisomal protein import machinery."xsd:string |
| http://purl.uniprot.org/citations/16679311 | http://purl.uniprot.org/core/title | "Pex19p-dependent targeting of Pex17p, a peripheral component of the peroxisomal protein import machinery."xsd:string |