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http://purl.uniprot.org/citations/16684532 | http://www.w3.org/2000/01/rdf-schema#comment | "BHC80 is a component of BRAF-HDAC complex (BHC) involved in transcriptional repression of neuron-specific genes in non-neuronal cells. However, BHC80 is present in both neuronal and non-neuronal cells. To explore the physiological importance of BHC80 in vivo, and the precise mechanism underlying neuron-specific gene repression by BHC80, we have produced mutant mice lacking Bhc80. The loss of Bhc80 resulted in neonatal lethality without sucking mother's breast milk sufficiently. Although Bhc80-deficient mice showed no developmental defect in the neuronal and non-neuronal tissues, Bhc80 is indispensable for the survival of neonatal pups."xsd:string |
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http://purl.uniprot.org/citations/16684532 | http://purl.uniprot.org/core/author | "Baba T."xsd:string |
http://purl.uniprot.org/citations/16684532 | http://purl.uniprot.org/core/author | "Takahashi S."xsd:string |
http://purl.uniprot.org/citations/16684532 | http://purl.uniprot.org/core/author | "Nakanishi T."xsd:string |
http://purl.uniprot.org/citations/16684532 | http://purl.uniprot.org/core/author | "Kashiwabara S."xsd:string |
http://purl.uniprot.org/citations/16684532 | http://purl.uniprot.org/core/author | "Honda A."xsd:string |
http://purl.uniprot.org/citations/16684532 | http://purl.uniprot.org/core/author | "Iwase S."xsd:string |
http://purl.uniprot.org/citations/16684532 | http://purl.uniprot.org/core/author | "Shono N."xsd:string |
http://purl.uniprot.org/citations/16684532 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
http://purl.uniprot.org/citations/16684532 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
http://purl.uniprot.org/citations/16684532 | http://purl.uniprot.org/core/pages | "3129-3135"xsd:string |
http://purl.uniprot.org/citations/16684532 | http://purl.uniprot.org/core/title | "A component of BRAF-HDAC complex, BHC80, is required for neonatal survival in mice."xsd:string |
http://purl.uniprot.org/citations/16684532 | http://purl.uniprot.org/core/volume | "580"xsd:string |
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