| http://purl.uniprot.org/citations/16687626 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16687626 | http://www.w3.org/2000/01/rdf-schema#comment | "The primary objectives of this analysis were to examine the effects of early posttransplantation (10 wk) serum levels of osteoprotegerin (OPG), mannose-binding lectin (MBL), and MBL-associated serine proteases (MASP; MASP-2 and MASP-3) on long-term (8-yr) patient survival, graft survival, and cardiovascular (CV) death. During a period of 16 mo (1995 to 1996), a total of 173 consecutive renal transplant recipients without diabetes before transplantation were included in a prospective study that was designed to address the impact of metabolic CV risk factors on survival and CV end points. Baseline sera from 172 patients were available for analysis. Follow-up data until January 1, 2004, were obtained from a national renal registry. Patients with high (fourth quartile) serum levels of OPG had significantly higher all-cause mortality (hazard ratio [HR] 6.3; 95% confidence interval [CI] 3.3 to 11.8; P<0.001) and CV death (HR 10.8; 95% CI 3.8 to 30.4; P<0.001) than patients with lower OPG concentrations. After multiple Cox regression analysis, high serum levels of OPG remained an independent predictor of all-cause mortality (HR 6.0; 95% CI 3.1 to 11.6, P<0.001) and CV death (HR 8.2; 95% CI 2.5 to 26.4; P<0.001). Multiple linear regression analysis revealed that age, creatinine clearance, and high-sensitivity C-reactive protein all were independently associated with OPG (R2=0.42). No significant association between OPG and death-censored graft loss was revealed. Serum levels of MBL, MASP-2, and MASP-3 were not significantly associated with patient survival, CV death, or graft loss. Early measured posttransplantation serum OPG is a highly significant independent predictor of death from any cause or CV death in white renal transplant recipients."xsd:string |
| http://purl.uniprot.org/citations/16687626 | http://purl.org/dc/terms/identifier | "doi:10.1681/asn.2005121368"xsd:string |
| http://purl.uniprot.org/citations/16687626 | http://purl.uniprot.org/core/author | "Hartmann A."xsd:string |
| http://purl.uniprot.org/citations/16687626 | http://purl.uniprot.org/core/author | "Thiel S."xsd:string |
| http://purl.uniprot.org/citations/16687626 | http://purl.uniprot.org/core/author | "Bollerslev J."xsd:string |
| http://purl.uniprot.org/citations/16687626 | http://purl.uniprot.org/core/author | "Ueland T."xsd:string |
| http://purl.uniprot.org/citations/16687626 | http://purl.uniprot.org/core/author | "Flyvbjerg A."xsd:string |
| http://purl.uniprot.org/citations/16687626 | http://purl.uniprot.org/core/author | "Hansen T.K."xsd:string |
| http://purl.uniprot.org/citations/16687626 | http://purl.uniprot.org/core/author | "Hjelmesaeth J."xsd:string |
| http://purl.uniprot.org/citations/16687626 | http://purl.uniprot.org/core/author | "Jenssen T."xsd:string |
| http://purl.uniprot.org/citations/16687626 | http://purl.uniprot.org/core/author | "Leivestad T."xsd:string |
| http://purl.uniprot.org/citations/16687626 | http://purl.uniprot.org/core/author | "Roislien J."xsd:string |
| http://purl.uniprot.org/citations/16687626 | http://purl.uniprot.org/core/author | "Sagedal S."xsd:string |
| http://purl.uniprot.org/citations/16687626 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16687626 | http://purl.uniprot.org/core/name | "J Am Soc Nephrol"xsd:string |
| http://purl.uniprot.org/citations/16687626 | http://purl.uniprot.org/core/pages | "1746-1754"xsd:string |
| http://purl.uniprot.org/citations/16687626 | http://purl.uniprot.org/core/title | "Early posttransplant serum osteoprotegerin levels predict long-term (8-year) patient survival and cardiovascular death in renal transplant patients."xsd:string |
| http://purl.uniprot.org/citations/16687626 | http://purl.uniprot.org/core/volume | "17"xsd:string |
| http://purl.uniprot.org/citations/16687626 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16687626 |
| http://purl.uniprot.org/citations/16687626 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16687626 |
| http://purl.uniprot.org/uniprot/#_O00300-mappedCitation-16687626 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16687626 |
| http://purl.uniprot.org/uniprot/O00300 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/16687626 |