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http://purl.uniprot.org/citations/16690745http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16690745http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16690745http://www.w3.org/2000/01/rdf-schema#comment"Mammalian oogenesis requires oocyte-specific transcriptional regulators. The full complement of oocyte-specific transcription factors is unknown. Here, we describe the finding that Sohlh1, a spermatogenesis and oogenesis basic helix-loop-helix transcription factor in females, is preferentially expressed in oocytes and required for oogenesis. Sohlh1 disruption perturbs follicular formation in part by causing down-regulation of two genes that are known to disrupt folliculogenesis: newborn ovary homeobox gene (Nobox) and factor in the germ-line alpha (Figla). In addition, we show that Lhx8 is downstream of Sohlh1 and critical in fertility. Thus, Sohlh1 and Lhx8 are two germ cell-specific, critical regulators of oogenesis."xsd:string
http://purl.uniprot.org/citations/16690745http://purl.org/dc/terms/identifier"doi:10.1073/pnas.0601083103"xsd:string
http://purl.uniprot.org/citations/16690745http://purl.org/dc/terms/identifier"doi:10.1073/pnas.0601083103"xsd:string
http://purl.uniprot.org/citations/16690745http://purl.uniprot.org/core/author"Zhao Y."xsd:string
http://purl.uniprot.org/citations/16690745http://purl.uniprot.org/core/author"Zhao Y."xsd:string
http://purl.uniprot.org/citations/16690745http://purl.uniprot.org/core/author"Choi Y."xsd:string
http://purl.uniprot.org/citations/16690745http://purl.uniprot.org/core/author"Choi Y."xsd:string
http://purl.uniprot.org/citations/16690745http://purl.uniprot.org/core/author"Rajkovic A."xsd:string
http://purl.uniprot.org/citations/16690745http://purl.uniprot.org/core/author"Rajkovic A."xsd:string
http://purl.uniprot.org/citations/16690745http://purl.uniprot.org/core/author"Matzuk M.M."xsd:string
http://purl.uniprot.org/citations/16690745http://purl.uniprot.org/core/author"Matzuk M.M."xsd:string
http://purl.uniprot.org/citations/16690745http://purl.uniprot.org/core/author"Westphal H."xsd:string
http://purl.uniprot.org/citations/16690745http://purl.uniprot.org/core/author"Westphal H."xsd:string
http://purl.uniprot.org/citations/16690745http://purl.uniprot.org/core/author"Pangas S.A."xsd:string
http://purl.uniprot.org/citations/16690745http://purl.uniprot.org/core/author"Pangas S.A."xsd:string
http://purl.uniprot.org/citations/16690745http://purl.uniprot.org/core/author"Ballow D.J."xsd:string
http://purl.uniprot.org/citations/16690745http://purl.uniprot.org/core/author"Ballow D.J."xsd:string
http://purl.uniprot.org/citations/16690745http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16690745http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16690745http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string
http://purl.uniprot.org/citations/16690745http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string
http://purl.uniprot.org/citations/16690745http://purl.uniprot.org/core/pages"8090-8095"xsd:string
http://purl.uniprot.org/citations/16690745http://purl.uniprot.org/core/pages"8090-8095"xsd:string