http://purl.uniprot.org/citations/16698994 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16698994 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16698994 | http://www.w3.org/2000/01/rdf-schema#comment | "The packaging of viral genomic RNA into nucleocapsids and subsequently into virions is not completely understood. Phosphoprotein (P) and nucleoprotein (NP) interactions link NP-RNA complexes with P-L (polymerase) complexes to form viral nucleocapsids. The nucleocapsid then interacts with the viral matrix protein, leading to specific packaging of the nucleocapsid into the virion. A mammalian two-hybrid assay and confocal microscopy were used to demonstrate that Ebola virus VP35 and VP40 interact and colocalize in transfected cells. VP35 was packaged into budding virus-like particles (VLPs) as observed by protease protection assays. Moreover, VP40 and VP35 were sufficient for packaging an Ebola virus minigenome RNA into VLPs. Results from immunoprecipitation-reverse transcriptase PCR experiments suggest that VP35 confers specificity of the nucleocapsid for viral genomic RNA by direct VP35-RNA interactions."xsd:string |
http://purl.uniprot.org/citations/16698994 | http://purl.org/dc/terms/identifier | "doi:10.1128/jvi.01857-05"xsd:string |
http://purl.uniprot.org/citations/16698994 | http://purl.org/dc/terms/identifier | "doi:10.1128/jvi.01857-05"xsd:string |
http://purl.uniprot.org/citations/16698994 | http://purl.uniprot.org/core/author | "Harty R.N."xsd:string |
http://purl.uniprot.org/citations/16698994 | http://purl.uniprot.org/core/author | "Harty R.N."xsd:string |
http://purl.uniprot.org/citations/16698994 | http://purl.uniprot.org/core/author | "McCarthy S.E."xsd:string |
http://purl.uniprot.org/citations/16698994 | http://purl.uniprot.org/core/author | "McCarthy S.E."xsd:string |
http://purl.uniprot.org/citations/16698994 | http://purl.uniprot.org/core/author | "Johnson R.F."xsd:string |
http://purl.uniprot.org/citations/16698994 | http://purl.uniprot.org/core/author | "Johnson R.F."xsd:string |
http://purl.uniprot.org/citations/16698994 | http://purl.uniprot.org/core/author | "Godlewski P.J."xsd:string |
http://purl.uniprot.org/citations/16698994 | http://purl.uniprot.org/core/author | "Godlewski P.J."xsd:string |
http://purl.uniprot.org/citations/16698994 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
http://purl.uniprot.org/citations/16698994 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
http://purl.uniprot.org/citations/16698994 | http://purl.uniprot.org/core/name | "J. Virol."xsd:string |
http://purl.uniprot.org/citations/16698994 | http://purl.uniprot.org/core/name | "J. Virol."xsd:string |
http://purl.uniprot.org/citations/16698994 | http://purl.uniprot.org/core/pages | "5135-5144"xsd:string |
http://purl.uniprot.org/citations/16698994 | http://purl.uniprot.org/core/pages | "5135-5144"xsd:string |
http://purl.uniprot.org/citations/16698994 | http://purl.uniprot.org/core/title | "Ebola virus VP35-VP40 interaction is sufficient for packaging 3E-5E minigenome RNA into virus-like particles."xsd:string |
http://purl.uniprot.org/citations/16698994 | http://purl.uniprot.org/core/title | "Ebola virus VP35-VP40 interaction is sufficient for packaging 3E-5E minigenome RNA into virus-like particles."xsd:string |
http://purl.uniprot.org/citations/16698994 | http://purl.uniprot.org/core/volume | "80"xsd:string |
http://purl.uniprot.org/citations/16698994 | http://purl.uniprot.org/core/volume | "80"xsd:string |
http://purl.uniprot.org/citations/16698994 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16698994 |
http://purl.uniprot.org/citations/16698994 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16698994 |