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http://purl.uniprot.org/citations/16709803http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16709803http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16709803http://www.w3.org/2000/01/rdf-schema#comment"MHC class I molecules exit the endoplasmic reticulum (ER) by an unknown mechanism. Although a selective export mechanism has been proposed for the anterograde transport of class I, a motif responsible for export has never been identified. Although classical class I molecules lacking their cytoplasmic tail are expressed on the cell surface, we found that HLA-F was entirely dependent on its cytoplasmic tail for export from the ER. Two known export motifs were recognizable in HLA-F. A C-terminal valine residue functioned in ER export and interacted with coat complex (COP)II, while an RxR motif also played an important role in anterograde transport and bound to 14-3-3 proteins. This divergent trafficking of HLA-F implicates an alternative function for HLA-F, independent of loading with peptides in the ER."xsd:string
http://purl.uniprot.org/citations/16709803http://purl.org/dc/terms/identifier"doi:10.4049/jimmunol.176.11.6464"xsd:string
http://purl.uniprot.org/citations/16709803http://purl.org/dc/terms/identifier"doi:10.4049/jimmunol.176.11.6464"xsd:string
http://purl.uniprot.org/citations/16709803http://purl.uniprot.org/core/author"Munro S."xsd:string
http://purl.uniprot.org/citations/16709803http://purl.uniprot.org/core/author"Munro S."xsd:string
http://purl.uniprot.org/citations/16709803http://purl.uniprot.org/core/author"Gillingham A.K."xsd:string
http://purl.uniprot.org/citations/16709803http://purl.uniprot.org/core/author"Gillingham A.K."xsd:string
http://purl.uniprot.org/citations/16709803http://purl.uniprot.org/core/author"Trowsdale J."xsd:string
http://purl.uniprot.org/citations/16709803http://purl.uniprot.org/core/author"Trowsdale J."xsd:string
http://purl.uniprot.org/citations/16709803http://purl.uniprot.org/core/author"Boyle L.H."xsd:string
http://purl.uniprot.org/citations/16709803http://purl.uniprot.org/core/author"Boyle L.H."xsd:string
http://purl.uniprot.org/citations/16709803http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16709803http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16709803http://purl.uniprot.org/core/name"J. Immunol."xsd:string
http://purl.uniprot.org/citations/16709803http://purl.uniprot.org/core/name"J. Immunol."xsd:string
http://purl.uniprot.org/citations/16709803http://purl.uniprot.org/core/pages"6464-6472"xsd:string
http://purl.uniprot.org/citations/16709803http://purl.uniprot.org/core/pages"6464-6472"xsd:string
http://purl.uniprot.org/citations/16709803http://purl.uniprot.org/core/title"Selective export of HLA-F by its cytoplasmic tail."xsd:string
http://purl.uniprot.org/citations/16709803http://purl.uniprot.org/core/title"Selective export of HLA-F by its cytoplasmic tail."xsd:string
http://purl.uniprot.org/citations/16709803http://purl.uniprot.org/core/volume"176"xsd:string
http://purl.uniprot.org/citations/16709803http://purl.uniprot.org/core/volume"176"xsd:string
http://purl.uniprot.org/citations/16709803http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16709803
http://purl.uniprot.org/citations/16709803http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16709803