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http://purl.uniprot.org/citations/16716206http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16716206http://www.w3.org/2000/01/rdf-schema#comment"Several lines of evidence suggest that metabolic changes in the kynurenic acid (KYNA) pathway are related to the etiology of schizophrenia. The inhibitor of kynurenine 3-monooxygenase (KMO) is known to increase KYNA levels, and the KMO gene is located in the chromosome region associated with schizophrenia, 1q42-q44. Single-marker and haplotype analyses for 6-tag single nucleotide polymorphisms (SNPs) of KMO were performed (cases = 465, controls = 440). Significant association of rs2275163 with schizophrenia was observed by single-marker comparisons (P = 0.032) and haplotype analysis including this SNP (P = 0.0049). Significant association of rs2275163 and haplotype was not replicated using a second, independent set of samples (cases = 480, controls = 448) (P = 0.706 and P = 0.689, respectively). These results suggest that the KMO is unlikely to be related to the development of schizophrenia in Japanese."xsd:string
http://purl.uniprot.org/citations/16716206http://purl.org/dc/terms/identifier"doi:10.1111/j.1601-183x.2006.00231.x"xsd:string
http://purl.uniprot.org/citations/16716206http://purl.uniprot.org/core/author"Ikeda M."xsd:string
http://purl.uniprot.org/citations/16716206http://purl.uniprot.org/core/author"Inada T."xsd:string
http://purl.uniprot.org/citations/16716206http://purl.uniprot.org/core/author"Miura H."xsd:string
http://purl.uniprot.org/citations/16716206http://purl.uniprot.org/core/author"Suzuki T."xsd:string
http://purl.uniprot.org/citations/16716206http://purl.uniprot.org/core/author"Yoshida K."xsd:string
http://purl.uniprot.org/citations/16716206http://purl.uniprot.org/core/author"Takahashi N."xsd:string
http://purl.uniprot.org/citations/16716206http://purl.uniprot.org/core/author"Saito S."xsd:string
http://purl.uniprot.org/citations/16716206http://purl.uniprot.org/core/author"Ji X."xsd:string
http://purl.uniprot.org/citations/16716206http://purl.uniprot.org/core/author"Kitajima T."xsd:string
http://purl.uniprot.org/citations/16716206http://purl.uniprot.org/core/author"Ozaki N."xsd:string
http://purl.uniprot.org/citations/16716206http://purl.uniprot.org/core/author"Iwata N."xsd:string
http://purl.uniprot.org/citations/16716206http://purl.uniprot.org/core/author"Yamanouchi Y."xsd:string
http://purl.uniprot.org/citations/16716206http://purl.uniprot.org/core/author"Aoyama N."xsd:string
http://purl.uniprot.org/citations/16716206http://purl.uniprot.org/core/author"Kinoshita Y."xsd:string
http://purl.uniprot.org/citations/16716206http://purl.uniprot.org/core/author"Ishihara R."xsd:string
http://purl.uniprot.org/citations/16716206http://purl.uniprot.org/core/author"Maeno N."xsd:string
http://purl.uniprot.org/citations/16716206http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16716206http://purl.uniprot.org/core/name"Genes Brain Behav"xsd:string
http://purl.uniprot.org/citations/16716206http://purl.uniprot.org/core/pages"364-368"xsd:string
http://purl.uniprot.org/citations/16716206http://purl.uniprot.org/core/title"Association study between kynurenine 3-monooxygenase gene and schizophrenia in the Japanese population."xsd:string
http://purl.uniprot.org/citations/16716206http://purl.uniprot.org/core/volume"5"xsd:string
http://purl.uniprot.org/citations/16716206http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16716206