| http://purl.uniprot.org/citations/16730350 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16730350 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16730350 | http://www.w3.org/2000/01/rdf-schema#comment | "It has been proposed that C. elegans LIN-9 functions downstream of CDK4 in a pathway that regulates cell proliferation. Here, we report that mammalian BARA/LIN-9 is a predominantly nuclear protein that inhibits cell proliferation. More importantly, we demonstrate that BARA/LIN-9 also acts downstream of cyclin D/CDK4 in mammalian cells since (i) its antiproliferative effect is partially blocked by coexpression of cyclin D1, and (ii) a mutant form that lacks the first 84 amino acids rescues several phenotypic alterations observed in mice null for cdk4. Interestingly, mutation of BARA/LIN-9 restores the expression of E2F target genes in CDK4 null MEFs, indicating that the wild-type protein plays a role in the expression of genes required for the G1/S transition."xsd:string |
| http://purl.uniprot.org/citations/16730350 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.yexcr.2006.04.002"xsd:string |
| http://purl.uniprot.org/citations/16730350 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.yexcr.2006.04.002"xsd:string |
| http://purl.uniprot.org/citations/16730350 | http://purl.uniprot.org/core/author | "Tian X."xsd:string |
| http://purl.uniprot.org/citations/16730350 | http://purl.uniprot.org/core/author | "Tian X."xsd:string |
| http://purl.uniprot.org/citations/16730350 | http://purl.uniprot.org/core/author | "Xue J."xsd:string |
| http://purl.uniprot.org/citations/16730350 | http://purl.uniprot.org/core/author | "Xue J."xsd:string |
| http://purl.uniprot.org/citations/16730350 | http://purl.uniprot.org/core/author | "Zou X."xsd:string |
| http://purl.uniprot.org/citations/16730350 | http://purl.uniprot.org/core/author | "Zou X."xsd:string |
| http://purl.uniprot.org/citations/16730350 | http://purl.uniprot.org/core/author | "Barrett K."xsd:string |
| http://purl.uniprot.org/citations/16730350 | http://purl.uniprot.org/core/author | "Barrett K."xsd:string |
| http://purl.uniprot.org/citations/16730350 | http://purl.uniprot.org/core/author | "Raychaudhuri P."xsd:string |
| http://purl.uniprot.org/citations/16730350 | http://purl.uniprot.org/core/author | "Raychaudhuri P."xsd:string |
| http://purl.uniprot.org/citations/16730350 | http://purl.uniprot.org/core/author | "Ucker D.S."xsd:string |
| http://purl.uniprot.org/citations/16730350 | http://purl.uniprot.org/core/author | "Ucker D.S."xsd:string |
| http://purl.uniprot.org/citations/16730350 | http://purl.uniprot.org/core/author | "Kiyokawa H."xsd:string |
| http://purl.uniprot.org/citations/16730350 | http://purl.uniprot.org/core/author | "Kiyokawa H."xsd:string |
| http://purl.uniprot.org/citations/16730350 | http://purl.uniprot.org/core/author | "Sandoval R."xsd:string |
| http://purl.uniprot.org/citations/16730350 | http://purl.uniprot.org/core/author | "Sandoval R."xsd:string |
| http://purl.uniprot.org/citations/16730350 | http://purl.uniprot.org/core/author | "Kineman R.D."xsd:string |
| http://purl.uniprot.org/citations/16730350 | http://purl.uniprot.org/core/author | "Kineman R.D."xsd:string |
| http://purl.uniprot.org/citations/16730350 | http://purl.uniprot.org/core/author | "Cook J.L."xsd:string |
| http://purl.uniprot.org/citations/16730350 | http://purl.uniprot.org/core/author | "Cook J.L."xsd:string |