| http://purl.uniprot.org/citations/16732290 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16732290 | http://www.w3.org/2000/01/rdf-schema#comment | "T cell activation involves the orchestration of several signaling pathways, including that of the 'classical' transcription factor NF-kappaB components NF-kappaB1-RelA. The function of the 'nonclassical' NF-kappaB2-RelB pathway is less clear, although T cells lacking components of this pathway have activation defects. Here we show that mice deficient in NF-kappaB-inducing kinase have a complex phenotype consisting of immunosuppression mediated by CD25(-)Foxp3(-) memory CD4(+) cells and, in the absence of those cells, hyper-responsive naive CD4(+) T cells, which caused autoimmune lesions after adoptive transfer into hosts deficient in recombination-activating genes. Biochemical studies indicated involvement of a cell-intrinsic mechanism in which NF-kappaB2 (p100) limits nuclear translocation of NF-kappaB1-RelA and thereby functions as a regulatory 'brake' for the activation of naive T cells."xsd:string |
| http://purl.uniprot.org/citations/16732290 | http://purl.org/dc/terms/identifier | "doi:10.1038/ni1351"xsd:string |
| http://purl.uniprot.org/citations/16732290 | http://purl.uniprot.org/core/author | "Hayashi Y."xsd:string |
| http://purl.uniprot.org/citations/16732290 | http://purl.uniprot.org/core/author | "Ishimaru N."xsd:string |
| http://purl.uniprot.org/citations/16732290 | http://purl.uniprot.org/core/author | "Sprent J."xsd:string |
| http://purl.uniprot.org/citations/16732290 | http://purl.uniprot.org/core/author | "Kishimoto H."xsd:string |
| http://purl.uniprot.org/citations/16732290 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16732290 | http://purl.uniprot.org/core/name | "Nat Immunol"xsd:string |
| http://purl.uniprot.org/citations/16732290 | http://purl.uniprot.org/core/pages | "763-772"xsd:string |
| http://purl.uniprot.org/citations/16732290 | http://purl.uniprot.org/core/title | "Regulation of naive T cell function by the NF-kappaB2 pathway."xsd:string |
| http://purl.uniprot.org/citations/16732290 | http://purl.uniprot.org/core/volume | "7"xsd:string |
| http://purl.uniprot.org/citations/16732290 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16732290 |
| http://purl.uniprot.org/citations/16732290 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16732290 |
| http://purl.uniprot.org/uniprot/#_A0A140LI24-mappedCitation-16732290 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16732290 |
| http://purl.uniprot.org/uniprot/#_A0A140LI46-mappedCitation-16732290 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16732290 |
| http://purl.uniprot.org/uniprot/#_A0A140LJD6-mappedCitation-16732290 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16732290 |
| http://purl.uniprot.org/uniprot/#_A0A494B9Y5-mappedCitation-16732290 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16732290 |
| http://purl.uniprot.org/uniprot/#_A0A494BAQ2-mappedCitation-16732290 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16732290 |
| http://purl.uniprot.org/uniprot/#_Q3UV15-mappedCitation-16732290 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16732290 |
| http://purl.uniprot.org/uniprot/#_Q4U105-mappedCitation-16732290 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16732290 |
| http://purl.uniprot.org/uniprot/#_Q4U106-mappedCitation-16732290 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16732290 |
| http://purl.uniprot.org/uniprot/#_Q4U108-mappedCitation-16732290 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16732290 |
| http://purl.uniprot.org/uniprot/#_Q4U109-mappedCitation-16732290 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16732290 |
| http://purl.uniprot.org/uniprot/#_Q4U110-mappedCitation-16732290 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16732290 |