| http://purl.uniprot.org/citations/16738937 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16738937 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16738937 | http://www.w3.org/2000/01/rdf-schema#comment | "Modo-UG is a class I gene located in the MHC of the marsupial Monodelphis domestica, the gray, short-tailed opossum. Modo-UG is expressed as three alternatively spliced mRNA forms, all of which encode a transmembrane form with a short cytoplasmic tail that lacks phosphorylation sites typically found in classical class I molecules. The three alternative mRNAs would encode a full-length form, an isoform lacking the alpha2 domain, and one lacking both alpha2 and alpha3 domains. Genotyping both captive-bred and wild M. domestica from different geographic regions revealed no variation in the residues that make up Modo-UG's peptide-binding groove. Modo-UG's low polymorphism is contrasting to that of a nearby class I locus, Modo-UA1, which has a highly polymorphic peptide-binding region. Absence of functional polymorphism in Modo-UG is therefore not a general feature of opossum class I genes but the result of negative selection. Modo-UG is the first MHC linked marsupial class I to be described that appears to clearly have nonclassical features."xsd:string |
| http://purl.uniprot.org/citations/16738937 | http://purl.org/dc/terms/identifier | "doi:10.1007/s00251-006-0115-4"xsd:string |
| http://purl.uniprot.org/citations/16738937 | http://purl.org/dc/terms/identifier | "doi:10.1007/s00251-006-0115-4"xsd:string |
| http://purl.uniprot.org/citations/16738937 | http://purl.uniprot.org/core/author | "Baker M.L."xsd:string |
| http://purl.uniprot.org/citations/16738937 | http://purl.uniprot.org/core/author | "Baker M.L."xsd:string |
| http://purl.uniprot.org/citations/16738937 | http://purl.uniprot.org/core/author | "Miller R.D."xsd:string |
| http://purl.uniprot.org/citations/16738937 | http://purl.uniprot.org/core/author | "Miller R.D."xsd:string |
| http://purl.uniprot.org/citations/16738937 | http://purl.uniprot.org/core/author | "Miska K.B."xsd:string |
| http://purl.uniprot.org/citations/16738937 | http://purl.uniprot.org/core/author | "Miska K.B."xsd:string |
| http://purl.uniprot.org/citations/16738937 | http://purl.uniprot.org/core/author | "Parra Z.E."xsd:string |
| http://purl.uniprot.org/citations/16738937 | http://purl.uniprot.org/core/author | "Parra Z.E."xsd:string |
| http://purl.uniprot.org/citations/16738937 | http://purl.uniprot.org/core/author | "Samollow P.B."xsd:string |
| http://purl.uniprot.org/citations/16738937 | http://purl.uniprot.org/core/author | "Samollow P.B."xsd:string |
| http://purl.uniprot.org/citations/16738937 | http://purl.uniprot.org/core/author | "Wright A.M."xsd:string |
| http://purl.uniprot.org/citations/16738937 | http://purl.uniprot.org/core/author | "Wright A.M."xsd:string |
| http://purl.uniprot.org/citations/16738937 | http://purl.uniprot.org/core/author | "Gouin N."xsd:string |
| http://purl.uniprot.org/citations/16738937 | http://purl.uniprot.org/core/author | "Gouin N."xsd:string |
| http://purl.uniprot.org/citations/16738937 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16738937 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16738937 | http://purl.uniprot.org/core/name | "Immunogenetics"xsd:string |
| http://purl.uniprot.org/citations/16738937 | http://purl.uniprot.org/core/name | "Immunogenetics"xsd:string |
| http://purl.uniprot.org/citations/16738937 | http://purl.uniprot.org/core/pages | "396-406"xsd:string |
| http://purl.uniprot.org/citations/16738937 | http://purl.uniprot.org/core/pages | "396-406"xsd:string |