| http://purl.uniprot.org/citations/16757563 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16757563 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16757563 | http://www.w3.org/2000/01/rdf-schema#comment | "Persistent hepatitis B virus infection is a major risk factor for hepatocellular carcinoma, the most frequent cancer in some developing countries. Up to 95% of those infected at birth and 15% of those infected after the neonatal period fail to clear hepatitis B virus, together resulting in approximately 350 million persistent carriers worldwide. Via a whole genome scan in Gambian families, we have identified a major susceptibility locus as a cluster of class II cytokine receptor genes on chromosome 21q22. Coding changes in two of these genes, the type I IFN receptor gene, IFN-AR2, and the IL-10RB gene that encodes a receptor chain for IL-10-related cytokines including the IFN-lambdas, are associated with viral clearance (haplotype P value = 0.0003), and in vitro assays support functional roles for these variants in receptor signaling."xsd:string |
| http://purl.uniprot.org/citations/16757563 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.0602800103"xsd:string |
| http://purl.uniprot.org/citations/16757563 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.0602800103"xsd:string |
| http://purl.uniprot.org/citations/16757563 | http://purl.uniprot.org/core/author | "Knapp S."xsd:string |
| http://purl.uniprot.org/citations/16757563 | http://purl.uniprot.org/core/author | "Knapp S."xsd:string |
| http://purl.uniprot.org/citations/16757563 | http://purl.uniprot.org/core/author | "Zhang L."xsd:string |
| http://purl.uniprot.org/citations/16757563 | http://purl.uniprot.org/core/author | "Zhang L."xsd:string |
| http://purl.uniprot.org/citations/16757563 | http://purl.uniprot.org/core/author | "Wright M."xsd:string |
| http://purl.uniprot.org/citations/16757563 | http://purl.uniprot.org/core/author | "Wright M."xsd:string |
| http://purl.uniprot.org/citations/16757563 | http://purl.uniprot.org/core/author | "Bell J.I."xsd:string |
| http://purl.uniprot.org/citations/16757563 | http://purl.uniprot.org/core/author | "Bell J.I."xsd:string |
| http://purl.uniprot.org/citations/16757563 | http://purl.uniprot.org/core/author | "Thomas H.C."xsd:string |
| http://purl.uniprot.org/citations/16757563 | http://purl.uniprot.org/core/author | "Thomas H.C."xsd:string |
| http://purl.uniprot.org/citations/16757563 | http://purl.uniprot.org/core/author | "Best S."xsd:string |
| http://purl.uniprot.org/citations/16757563 | http://purl.uniprot.org/core/author | "Best S."xsd:string |
| http://purl.uniprot.org/citations/16757563 | http://purl.uniprot.org/core/author | "Graves M."xsd:string |
| http://purl.uniprot.org/citations/16757563 | http://purl.uniprot.org/core/author | "Graves M."xsd:string |
| http://purl.uniprot.org/citations/16757563 | http://purl.uniprot.org/core/author | "Chiaramonte M."xsd:string |
| http://purl.uniprot.org/citations/16757563 | http://purl.uniprot.org/core/author | "Chiaramonte M."xsd:string |
| http://purl.uniprot.org/citations/16757563 | http://purl.uniprot.org/core/author | "Dumpis U."xsd:string |
| http://purl.uniprot.org/citations/16757563 | http://purl.uniprot.org/core/author | "Dumpis U."xsd:string |
| http://purl.uniprot.org/citations/16757563 | http://purl.uniprot.org/core/author | "Durham A."xsd:string |
| http://purl.uniprot.org/citations/16757563 | http://purl.uniprot.org/core/author | "Durham A."xsd:string |