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http://purl.uniprot.org/citations/16774934http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16774934http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16774934http://www.w3.org/2000/01/rdf-schema#comment"Fifty single-nucleotide polymorphisms (SNPs) associated with amino acid changes in 36 genes involved in diverse DNA repair pathways were assessed for associations with risk for small cell lung carcinoma (SCLC) by a case-control study consisting of 211 SCLC cases and 685 controls. An SNP, Val83Met, in the MTH1 (microtT homolog 1) gene encoding a triphosphatase that hydrolyzes pro-mutagenic oxidized nucleoside triphosphates, such as 8-hydroxy-dGTP and 2-hydroxy-dATP, showed the strongest and a significant association with SCLC risk [odds ratio (OR)=1.6, 95% confidence interval (CI): 1.2-2.2, P=0.004], while three other SNPs in the TP53, BLM and SNM1 genes, respectively, also showed marginal associations (0.05xsd:string
http://purl.uniprot.org/citations/16774934http://purl.org/dc/terms/identifier"doi:10.1093/carcin/bgl095"xsd:string
http://purl.uniprot.org/citations/16774934http://purl.org/dc/terms/identifier"doi:10.1093/carcin/bgl095"xsd:string
http://purl.uniprot.org/citations/16774934http://purl.uniprot.org/core/author"Goto K."xsd:string
http://purl.uniprot.org/citations/16774934http://purl.uniprot.org/core/author"Goto K."xsd:string
http://purl.uniprot.org/citations/16774934http://purl.uniprot.org/core/author"Ohta T."xsd:string
http://purl.uniprot.org/citations/16774934http://purl.uniprot.org/core/author"Ohta T."xsd:string
http://purl.uniprot.org/citations/16774934http://purl.uniprot.org/core/author"Yamamoto S."xsd:string
http://purl.uniprot.org/citations/16774934http://purl.uniprot.org/core/author"Yamamoto S."xsd:string
http://purl.uniprot.org/citations/16774934http://purl.uniprot.org/core/author"Eguchi T."xsd:string
http://purl.uniprot.org/citations/16774934http://purl.uniprot.org/core/author"Eguchi T."xsd:string
http://purl.uniprot.org/citations/16774934http://purl.uniprot.org/core/author"Hirose H."xsd:string
http://purl.uniprot.org/citations/16774934http://purl.uniprot.org/core/author"Hirose H."xsd:string
http://purl.uniprot.org/citations/16774934http://purl.uniprot.org/core/author"Kohno T."xsd:string
http://purl.uniprot.org/citations/16774934http://purl.uniprot.org/core/author"Kohno T."xsd:string
http://purl.uniprot.org/citations/16774934http://purl.uniprot.org/core/author"Kuchiba A."xsd:string
http://purl.uniprot.org/citations/16774934http://purl.uniprot.org/core/author"Kuchiba A."xsd:string
http://purl.uniprot.org/citations/16774934http://purl.uniprot.org/core/author"Kunitoh H."xsd:string
http://purl.uniprot.org/citations/16774934http://purl.uniprot.org/core/author"Kunitoh H."xsd:string
http://purl.uniprot.org/citations/16774934http://purl.uniprot.org/core/author"Mimaki S."xsd:string
http://purl.uniprot.org/citations/16774934http://purl.uniprot.org/core/author"Mimaki S."xsd:string
http://purl.uniprot.org/citations/16774934http://purl.uniprot.org/core/author"Nishiwaki Y."xsd:string
http://purl.uniprot.org/citations/16774934http://purl.uniprot.org/core/author"Nishiwaki Y."xsd:string