| http://purl.uniprot.org/citations/16785321 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16785321 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16785321 | http://www.w3.org/2000/01/rdf-schema#comment | "Centrins are calmodulin-like proteins present in centrosomes and yeast spindle pole bodies (SPBs) and have essential functions in their duplication. The Saccharomyces cerevisiae centrin, Cdc31p, binds Sfi1p on multiple conserved repeats; both proteins localize to the SPB half-bridge, where the new SPB is assembled. The crystal structures of Sfi1p-centrin complexes containing several repeats show Sfi1p as an alpha helix with centrins wrapped around each repeat and similar centrin-centrin contacts between each repeat. Electron microscopy (EM) shadowing of an Sfi1p-centrin complex with 15 Sfi1 repeats and 15 centrins bound showed filaments 60 nm long, compatible with all the Sfi1 repeats as a continuous alpha helix. Immuno-EM localization of the Sfi1p N and C termini showed Sfi1p-centrin filaments spanning the length of the half-bridge with the Sfi1p N terminus at the SPB. This suggests a model for SPB duplication where the half-bridge doubles in length by association of the Sfi1p C termini, thereby providing a new Sfi1p N terminus to initiate SPB assembly."xsd:string |
| http://purl.uniprot.org/citations/16785321 | http://purl.org/dc/terms/identifier | "doi:10.1083/jcb.200603153"xsd:string |
| http://purl.uniprot.org/citations/16785321 | http://purl.org/dc/terms/identifier | "doi:10.1083/jcb.200603153"xsd:string |
| http://purl.uniprot.org/citations/16785321 | http://purl.uniprot.org/core/author | "Li S."xsd:string |
| http://purl.uniprot.org/citations/16785321 | http://purl.uniprot.org/core/author | "Li S."xsd:string |
| http://purl.uniprot.org/citations/16785321 | http://purl.uniprot.org/core/author | "Robinson C.V."xsd:string |
| http://purl.uniprot.org/citations/16785321 | http://purl.uniprot.org/core/author | "Robinson C.V."xsd:string |
| http://purl.uniprot.org/citations/16785321 | http://purl.uniprot.org/core/author | "Williams R.L."xsd:string |
| http://purl.uniprot.org/citations/16785321 | http://purl.uniprot.org/core/author | "Williams R.L."xsd:string |
| http://purl.uniprot.org/citations/16785321 | http://purl.uniprot.org/core/author | "Kilmartin J.V."xsd:string |
| http://purl.uniprot.org/citations/16785321 | http://purl.uniprot.org/core/author | "Kilmartin J.V."xsd:string |
| http://purl.uniprot.org/citations/16785321 | http://purl.uniprot.org/core/author | "Sandercock A.M."xsd:string |
| http://purl.uniprot.org/citations/16785321 | http://purl.uniprot.org/core/author | "Sandercock A.M."xsd:string |
| http://purl.uniprot.org/citations/16785321 | http://purl.uniprot.org/core/author | "Conduit P."xsd:string |
| http://purl.uniprot.org/citations/16785321 | http://purl.uniprot.org/core/author | "Conduit P."xsd:string |
| http://purl.uniprot.org/citations/16785321 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16785321 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16785321 | http://purl.uniprot.org/core/name | "J. Cell Biol."xsd:string |
| http://purl.uniprot.org/citations/16785321 | http://purl.uniprot.org/core/name | "J. Cell Biol."xsd:string |
| http://purl.uniprot.org/citations/16785321 | http://purl.uniprot.org/core/pages | "867-877"xsd:string |
| http://purl.uniprot.org/citations/16785321 | http://purl.uniprot.org/core/pages | "867-877"xsd:string |
| http://purl.uniprot.org/citations/16785321 | http://purl.uniprot.org/core/title | "Structural role of Sfi1p-centrin filaments in budding yeast spindle pole body duplication."xsd:string |
| http://purl.uniprot.org/citations/16785321 | http://purl.uniprot.org/core/title | "Structural role of Sfi1p-centrin filaments in budding yeast spindle pole body duplication."xsd:string |