| http://purl.uniprot.org/citations/1678600 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1678600 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1678600 | http://www.w3.org/2000/01/rdf-schema#comment | "Malignant human glioma D-298 MG amplifies a rearranged epidermal growth factor receptor (EGFR) gene (c-erbB proto-oncogene), resulting in an in-frame deletion of 83 amino acids in domain IV of the extracellular domain of the EGFR. EGF and transforming growth factor-a (TGF-a) bound to the mutant EGFR with high affinity and enhanced the intrinsic mutant EGFR kinase activity. The mutant EGFR was capable of transducing EGF-stimulated glioma cell proliferation and invasiveness in an in vitro three-dimensional spheroid model. The deletion-mutant EGFR in D-298 MG is capable of being activated by growth factor; this suggests that overexpression of this mutant EGFR protein rather than structural alteration may be the more significant biologic event."xsd:string |
| http://purl.uniprot.org/citations/1678600 | http://purl.org/dc/terms/identifier | "doi:10.1016/0006-291X(91)91051-D"xsd:string |
| http://purl.uniprot.org/citations/1678600 | http://purl.org/dc/terms/identifier | "doi:10.1016/0006-291x(91)91051-d"xsd:string |
| http://purl.uniprot.org/citations/1678600 | http://purl.uniprot.org/core/author | "Bigner D.D."xsd:string |
| http://purl.uniprot.org/citations/1678600 | http://purl.uniprot.org/core/author | "Bigner D.D."xsd:string |
| http://purl.uniprot.org/citations/1678600 | http://purl.uniprot.org/core/author | "Wong A.J."xsd:string |
| http://purl.uniprot.org/citations/1678600 | http://purl.uniprot.org/core/author | "Wong A.J."xsd:string |
| http://purl.uniprot.org/citations/1678600 | http://purl.uniprot.org/core/author | "Bjerkvig R."xsd:string |
| http://purl.uniprot.org/citations/1678600 | http://purl.uniprot.org/core/author | "Bjerkvig R."xsd:string |
| http://purl.uniprot.org/citations/1678600 | http://purl.uniprot.org/core/author | "Archer G.E."xsd:string |
| http://purl.uniprot.org/citations/1678600 | http://purl.uniprot.org/core/author | "Archer G.E."xsd:string |
| http://purl.uniprot.org/citations/1678600 | http://purl.uniprot.org/core/author | "Friedman H.S."xsd:string |
| http://purl.uniprot.org/citations/1678600 | http://purl.uniprot.org/core/author | "Friedman H.S."xsd:string |
| http://purl.uniprot.org/citations/1678600 | http://purl.uniprot.org/core/author | "Gangarosa L.M."xsd:string |
| http://purl.uniprot.org/citations/1678600 | http://purl.uniprot.org/core/author | "Gangarosa L.M."xsd:string |
| http://purl.uniprot.org/citations/1678600 | http://purl.uniprot.org/core/author | "Humphrey P.A."xsd:string |
| http://purl.uniprot.org/citations/1678600 | http://purl.uniprot.org/core/author | "Humphrey P.A."xsd:string |
| http://purl.uniprot.org/citations/1678600 | http://purl.uniprot.org/core/author | "Laerum O.D."xsd:string |
| http://purl.uniprot.org/citations/1678600 | http://purl.uniprot.org/core/author | "Laerum O.D."xsd:string |
| http://purl.uniprot.org/citations/1678600 | http://purl.uniprot.org/core/author | "Lund-Johansen M."xsd:string |
| http://purl.uniprot.org/citations/1678600 | http://purl.uniprot.org/core/author | "Lund-Johansen M."xsd:string |
| http://purl.uniprot.org/citations/1678600 | http://purl.uniprot.org/core/date | "1991"xsd:gYear |
| http://purl.uniprot.org/citations/1678600 | http://purl.uniprot.org/core/date | "1991"xsd:gYear |