| http://purl.uniprot.org/citations/16794080 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16794080 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16794080 | http://www.w3.org/2000/01/rdf-schema#comment | "The formation of the neuromuscular synapse requires muscle-specific receptor kinase (MuSK) to orchestrate postsynaptic differentiation, including the clustering of receptors for the neurotransmitter acetylcholine. Upon innervation, neural agrin activates MuSK to establish the postsynaptic apparatus, although agrin-independent formation of neuromuscular synapses can also occur experimentally in the absence of neurotransmission. Dok-7, a MuSK-interacting cytoplasmic protein, is essential for MuSK activation in cultured myotubes; in particular, the Dok-7 phosphotyrosine-binding domain and its target in MuSK are indispensable. Mice lacking Dok-7 formed neither acetylcholine receptor clusters nor neuromuscular synapses. Thus, Dok-7 is essential for neuromuscular synaptogenesis through its interaction with MuSK."xsd:string |
| http://purl.uniprot.org/citations/16794080 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1127142"xsd:string |
| http://purl.uniprot.org/citations/16794080 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1127142"xsd:string |
| http://purl.uniprot.org/citations/16794080 | http://purl.uniprot.org/core/author | "Kubo S."xsd:string |
| http://purl.uniprot.org/citations/16794080 | http://purl.uniprot.org/core/author | "Kubo S."xsd:string |
| http://purl.uniprot.org/citations/16794080 | http://purl.uniprot.org/core/author | "Inoue A."xsd:string |
| http://purl.uniprot.org/citations/16794080 | http://purl.uniprot.org/core/author | "Inoue A."xsd:string |
| http://purl.uniprot.org/citations/16794080 | http://purl.uniprot.org/core/author | "Murata Y."xsd:string |
| http://purl.uniprot.org/citations/16794080 | http://purl.uniprot.org/core/author | "Murata Y."xsd:string |
| http://purl.uniprot.org/citations/16794080 | http://purl.uniprot.org/core/author | "Okada K."xsd:string |
| http://purl.uniprot.org/citations/16794080 | http://purl.uniprot.org/core/author | "Okada K."xsd:string |
| http://purl.uniprot.org/citations/16794080 | http://purl.uniprot.org/core/author | "Okada M."xsd:string |
| http://purl.uniprot.org/citations/16794080 | http://purl.uniprot.org/core/author | "Okada M."xsd:string |
| http://purl.uniprot.org/citations/16794080 | http://purl.uniprot.org/core/author | "Shiraishi H."xsd:string |
| http://purl.uniprot.org/citations/16794080 | http://purl.uniprot.org/core/author | "Shiraishi H."xsd:string |
| http://purl.uniprot.org/citations/16794080 | http://purl.uniprot.org/core/author | "Yamanashi Y."xsd:string |
| http://purl.uniprot.org/citations/16794080 | http://purl.uniprot.org/core/author | "Yamanashi Y."xsd:string |
| http://purl.uniprot.org/citations/16794080 | http://purl.uniprot.org/core/author | "Akiyama T."xsd:string |
| http://purl.uniprot.org/citations/16794080 | http://purl.uniprot.org/core/author | "Akiyama T."xsd:string |
| http://purl.uniprot.org/citations/16794080 | http://purl.uniprot.org/core/author | "Iwakura Y."xsd:string |
| http://purl.uniprot.org/citations/16794080 | http://purl.uniprot.org/core/author | "Iwakura Y."xsd:string |
| http://purl.uniprot.org/citations/16794080 | http://purl.uniprot.org/core/author | "Kakuta S."xsd:string |
| http://purl.uniprot.org/citations/16794080 | http://purl.uniprot.org/core/author | "Kakuta S."xsd:string |