| http://purl.uniprot.org/citations/16819554 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16819554 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16819554 | http://www.w3.org/2000/01/rdf-schema#comment | "Forkhead transcription factors are key participants in development and immune regulation. Here we demonstrate that absence of the gene encoding the forkhead transcription factor Foxp1 resulted in a profound defect in early B cell development. Foxp1 deficiency was associated with decreased expression of all B lineage genes in B220+ fetal liver cells as well as with a block in the transition from pro-B cell to pre-B cell involving diminished expression of recombination-activating genes 1 and 2. Foxp1 bound to the Erag enhancer and was involved in controlling variable-(diversity)-joining recombination of the gene encoding immunoglobulin heavy chain in a B cell lineage-specific way. Our results identify Foxp1 as an essential participant in the transcriptional regulatory network of B lymphopoiesis."xsd:string |
| http://purl.uniprot.org/citations/16819554 | http://purl.org/dc/terms/identifier | "doi:10.1038/ni1358"xsd:string |
| http://purl.uniprot.org/citations/16819554 | http://purl.org/dc/terms/identifier | "doi:10.1038/ni1358"xsd:string |
| http://purl.uniprot.org/citations/16819554 | http://purl.uniprot.org/core/author | "Hu H."xsd:string |
| http://purl.uniprot.org/citations/16819554 | http://purl.uniprot.org/core/author | "Hu H."xsd:string |
| http://purl.uniprot.org/citations/16819554 | http://purl.uniprot.org/core/author | "Wang B."xsd:string |
| http://purl.uniprot.org/citations/16819554 | http://purl.uniprot.org/core/author | "Wang B."xsd:string |
| http://purl.uniprot.org/citations/16819554 | http://purl.uniprot.org/core/author | "Rao A."xsd:string |
| http://purl.uniprot.org/citations/16819554 | http://purl.uniprot.org/core/author | "Rao A."xsd:string |
| http://purl.uniprot.org/citations/16819554 | http://purl.uniprot.org/core/author | "Tucker P.W."xsd:string |
| http://purl.uniprot.org/citations/16819554 | http://purl.uniprot.org/core/author | "Tucker P.W."xsd:string |
| http://purl.uniprot.org/citations/16819554 | http://purl.uniprot.org/core/author | "Nardone J."xsd:string |
| http://purl.uniprot.org/citations/16819554 | http://purl.uniprot.org/core/author | "Nardone J."xsd:string |
| http://purl.uniprot.org/citations/16819554 | http://purl.uniprot.org/core/author | "Allred L."xsd:string |
| http://purl.uniprot.org/citations/16819554 | http://purl.uniprot.org/core/author | "Allred L."xsd:string |
| http://purl.uniprot.org/citations/16819554 | http://purl.uniprot.org/core/author | "Borde M."xsd:string |
| http://purl.uniprot.org/citations/16819554 | http://purl.uniprot.org/core/author | "Borde M."xsd:string |
| http://purl.uniprot.org/citations/16819554 | http://purl.uniprot.org/core/author | "Maika S."xsd:string |
| http://purl.uniprot.org/citations/16819554 | http://purl.uniprot.org/core/author | "Maika S."xsd:string |
| http://purl.uniprot.org/citations/16819554 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16819554 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16819554 | http://purl.uniprot.org/core/name | "Nat. Immunol."xsd:string |
| http://purl.uniprot.org/citations/16819554 | http://purl.uniprot.org/core/name | "Nat. Immunol."xsd:string |