| http://purl.uniprot.org/citations/16823370 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16823370 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16823370 | http://www.w3.org/2000/01/rdf-schema#comment | "Antifreeze proteins (AFPs) are found in cold-adapted organisms and have the unusual ability to bind to and inhibit the growth of ice crystals. However, the underlying molecular basis of their ice-binding activity is unclear because of the difficulty of studying the AFP-ice interaction directly and the lack of a common motif, domain or fold among different AFPs. We have formulated a generic ice-binding model and incorporated it into a physicochemical pattern-recognition algorithm. It successfully recognizes ice-binding surfaces for a diverse range of AFPs, and clearly discriminates AFPs from other structures in the Protein Data Bank. The algorithm was used to identify a novel AFP from winter rye, and the antifreeze activity of this protein was subsequently confirmed. The presence of a common and distinct physicochemical pattern provides a structural basis for unifying AFPs from fish, insects and plants."xsd:string |
| http://purl.uniprot.org/citations/16823370 | http://purl.org/dc/terms/identifier | "doi:10.1038/nbt1224"xsd:string |
| http://purl.uniprot.org/citations/16823370 | http://purl.org/dc/terms/identifier | "doi:10.1038/nbt1224"xsd:string |
| http://purl.uniprot.org/citations/16823370 | http://purl.uniprot.org/core/author | "Doxey A.C."xsd:string |
| http://purl.uniprot.org/citations/16823370 | http://purl.uniprot.org/core/author | "Doxey A.C."xsd:string |
| http://purl.uniprot.org/citations/16823370 | http://purl.uniprot.org/core/author | "Griffith M."xsd:string |
| http://purl.uniprot.org/citations/16823370 | http://purl.uniprot.org/core/author | "Griffith M."xsd:string |
| http://purl.uniprot.org/citations/16823370 | http://purl.uniprot.org/core/author | "Yaish M.W."xsd:string |
| http://purl.uniprot.org/citations/16823370 | http://purl.uniprot.org/core/author | "Yaish M.W."xsd:string |
| http://purl.uniprot.org/citations/16823370 | http://purl.uniprot.org/core/author | "McConkey B.J."xsd:string |
| http://purl.uniprot.org/citations/16823370 | http://purl.uniprot.org/core/author | "McConkey B.J."xsd:string |
| http://purl.uniprot.org/citations/16823370 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16823370 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16823370 | http://purl.uniprot.org/core/name | "Nat. Biotechnol."xsd:string |
| http://purl.uniprot.org/citations/16823370 | http://purl.uniprot.org/core/name | "Nat Biotechnol"xsd:string |
| http://purl.uniprot.org/citations/16823370 | http://purl.uniprot.org/core/pages | "852-855"xsd:string |
| http://purl.uniprot.org/citations/16823370 | http://purl.uniprot.org/core/pages | "852-855"xsd:string |
| http://purl.uniprot.org/citations/16823370 | http://purl.uniprot.org/core/title | "Ordered surface carbons distinguish antifreeze proteins and their ice-binding regions."xsd:string |
| http://purl.uniprot.org/citations/16823370 | http://purl.uniprot.org/core/title | "Ordered surface carbons distinguish antifreeze proteins and their ice-binding regions."xsd:string |
| http://purl.uniprot.org/citations/16823370 | http://purl.uniprot.org/core/volume | "24"xsd:string |
| http://purl.uniprot.org/citations/16823370 | http://purl.uniprot.org/core/volume | "24"xsd:string |
| http://purl.uniprot.org/citations/16823370 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16823370 |
| http://purl.uniprot.org/citations/16823370 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16823370 |