http://purl.uniprot.org/citations/16827183 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16827183 | http://www.w3.org/2000/01/rdf-schema#comment | "ObjectiveTo evaluate the alterations of biomarkers in the development and progression of coal workers' pneumoconiosis (CWP).MethodsThe type and number of cells, and the levels of tumor necrosis factor-alpha (TNF-alpha), pulmonary surfactant protein, phospholipids and fibronectin in bronchoalveolar lavage fluid were assayed in 14 health active coal miners, 21 coal miners without CWP and 13 miners with CWP of 0/1 to 1/1.ResultsCompared to active coal miners without CWP (8.23 microg/mL), TNF-alpha concentration was gradually decreased when dust exposure was stopped (5.90 microg/mL). Elevated surfactant protein A (SP-A) level and phosphatidylglycerol (PG) to phosphatidylinositol (PI) ratio were found in miners actively exposed to coal dust (6528 ng/mL for SP-A and 10. for PG/PI), and both parameters decreased when CWP progressed from CWP (0/1) (3419 microg/mL for SP-A and 5.9 for PG/PI) to CWP (1/1) (1654 microg/mL for SP-A and 5.5 for PG/PI).ConclusionBiomarkers in bronchoalveolar lavage fluid can be used to screen coal miners at high risk of developing coal workers' pneumoconiosis."xsd:string |
http://purl.uniprot.org/citations/16827183 | http://purl.uniprot.org/core/author | "Chen W.H."xsd:string |
http://purl.uniprot.org/citations/16827183 | http://purl.uniprot.org/core/author | "Bruch J."xsd:string |
http://purl.uniprot.org/citations/16827183 | http://purl.uniprot.org/core/author | "Xing J.C."xsd:string |
http://purl.uniprot.org/citations/16827183 | http://purl.uniprot.org/core/author | "Guo M.F."xsd:string |
http://purl.uniprot.org/citations/16827183 | http://purl.uniprot.org/core/author | "Han W.H."xsd:string |
http://purl.uniprot.org/citations/16827183 | http://purl.uniprot.org/core/author | "Rehn S."xsd:string |
http://purl.uniprot.org/citations/16827183 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
http://purl.uniprot.org/citations/16827183 | http://purl.uniprot.org/core/name | "Biomed Environ Sci"xsd:string |
http://purl.uniprot.org/citations/16827183 | http://purl.uniprot.org/core/pages | "124-129"xsd:string |
http://purl.uniprot.org/citations/16827183 | http://purl.uniprot.org/core/title | "Changes of tumor necrosis factor, surfactant protein A, and phospholipids in bronchoalveolar lavage fluid in the development and progression of coal workers' pneumoconiosis."xsd:string |
http://purl.uniprot.org/citations/16827183 | http://purl.uniprot.org/core/volume | "19"xsd:string |
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