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| http://purl.uniprot.org/citations/16837044 | http://www.w3.org/2000/01/rdf-schema#comment | "AML patients with normal karyotype comprise the largest subgroup ( approximately 50%) but have a highly heterogeneous clinical course. By multi-parameter flow cytometry we analyzed CD7 expression along with other phenotypic markers in 185 patients with normal-karyotype AML. CD7 was expressed in 68 (37%) patients. CD7 expression was associated with younger age (P=0.024) but not with sex, WBC count, or extramedullary disease. Patients expressing CD7 had significant shorter disease free (DFS) and post-remission survivals (PRS) than patients without CD7 (DFS of 12 months versus 42 months, P=0.005; PRS of 15 months versus 33 months, P=0.013). We also found that expression of CD34 or HLA-DR was associated with lower CR rate (P=0.0007 and P=0.019, respectively) but did not affect DFS or OS. Furthermore, as for all AML patients, we demonstrated that in the normal karyotypic subgroup, patients with higher WBC counts (>50) and older age (>60 years) had lower CR rate (P=0.003 and P=0.0157, respectively) and shorter OS (Pxsd:string |
| http://purl.uniprot.org/citations/16837044 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.leukres.2006.06.001"xsd:string |
| http://purl.uniprot.org/citations/16837044 | http://purl.uniprot.org/core/author | "Chang H."xsd:string |
| http://purl.uniprot.org/citations/16837044 | http://purl.uniprot.org/core/author | "Yeung J."xsd:string |
| http://purl.uniprot.org/citations/16837044 | http://purl.uniprot.org/core/author | "Brandwein J."xsd:string |
| http://purl.uniprot.org/citations/16837044 | http://purl.uniprot.org/core/author | "Yi Q.L."xsd:string |
| http://purl.uniprot.org/citations/16837044 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/16837044 | http://purl.uniprot.org/core/name | "Leuk Res"xsd:string |
| http://purl.uniprot.org/citations/16837044 | http://purl.uniprot.org/core/pages | "157-162"xsd:string |
| http://purl.uniprot.org/citations/16837044 | http://purl.uniprot.org/core/title | "CD7 expression predicts poor disease free survival and post-remission survival in patients with acute myeloid leukemia and normal karyotype."xsd:string |
| http://purl.uniprot.org/citations/16837044 | http://purl.uniprot.org/core/volume | "31"xsd:string |
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