http://purl.uniprot.org/citations/16847139 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16847139 | http://www.w3.org/2000/01/rdf-schema#comment | "Phage P4 int gene encodes the integrase responsible for phage integration into and excision from the Escherichia coli chromosome. Here, the data showing that P4 int expression is regulated in a complex manner at different levels are presented. First of all, the Pint promoter is regulated negatively by both Int and Vis, the P4 excisionase. The N-terminal portion of Int appears to be sufficient for such a negative autoregulation, suggesting that the Int N terminus is implicated in DNA binding. Second, full-length transcripts covering the entire int gene could be detected only upon P4 infection, whereas in P4 lysogens only short 5'-end covering transcripts were detectable. On the other hand, transcripts covering the 5'-end of int were also very abundant upon infection. It thus appears that premature transcription termination and/or mRNA degradation play a role in Int-negative regulation both on the basal prophage transcription and upon infection. Finally, comparison between Pint-lacZ transcriptional and translational fusions suggests that Vis regulates Int expression post-transcriptionally. The findings that Vis is also an RNA-binding protein and that Int may be translated from two different start codons have implications on possible regulation models of Int expression."xsd:string |
http://purl.uniprot.org/citations/16847139 | http://purl.org/dc/terms/identifier | "doi:10.1099/vir.0.81875-0"xsd:string |
http://purl.uniprot.org/citations/16847139 | http://purl.uniprot.org/core/author | "Sala C."xsd:string |
http://purl.uniprot.org/citations/16847139 | http://purl.uniprot.org/core/author | "Deho G."xsd:string |
http://purl.uniprot.org/citations/16847139 | http://purl.uniprot.org/core/author | "Ghisotti D."xsd:string |
http://purl.uniprot.org/citations/16847139 | http://purl.uniprot.org/core/author | "Forti F."xsd:string |
http://purl.uniprot.org/citations/16847139 | http://purl.uniprot.org/core/author | "Piazzolla D."xsd:string |
http://purl.uniprot.org/citations/16847139 | http://purl.uniprot.org/core/author | "Cali S."xsd:string |
http://purl.uniprot.org/citations/16847139 | http://purl.uniprot.org/core/author | "Magnoni F."xsd:string |
http://purl.uniprot.org/citations/16847139 | http://purl.uniprot.org/core/author | "Spoldi E."xsd:string |
http://purl.uniprot.org/citations/16847139 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
http://purl.uniprot.org/citations/16847139 | http://purl.uniprot.org/core/name | "J Gen Virol"xsd:string |
http://purl.uniprot.org/citations/16847139 | http://purl.uniprot.org/core/pages | "2423-2431"xsd:string |
http://purl.uniprot.org/citations/16847139 | http://purl.uniprot.org/core/title | "Expression of phage P4 integrase is regulated negatively by both Int and Vis."xsd:string |
http://purl.uniprot.org/citations/16847139 | http://purl.uniprot.org/core/volume | "87"xsd:string |
http://purl.uniprot.org/citations/16847139 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16847139 |
http://purl.uniprot.org/citations/16847139 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16847139 |
http://purl.uniprot.org/uniprot/P08320#attribution-478230C712ED69B4A5D5A4C9A27D8136 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/16847139 |
http://purl.uniprot.org/uniprot/#_P08320-mappedCitation-16847139 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16847139 |
http://purl.uniprot.org/uniprot/#_P12552-mappedCitation-16847139 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16847139 |
http://purl.uniprot.org/uniprot/P12552 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/16847139 |
http://purl.uniprot.org/uniprot/P08320 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/16847139 |