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http://purl.uniprot.org/citations/16859641http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16859641http://www.w3.org/2000/01/rdf-schema#comment"To study the mechanism of the inhibitory effects of Sef (similar expression to fgf genes) on Ras/mitogen-activated protein kinase (MAPK) signaling pathway, we observed cellular localization of this protein. Immunofluorescent staining results show that Sef locates in the vesicles of the cytoplasm without bFGF treatment but co-localizes with Ras on the plasma membrane (PM) in response to bFGF stimulation. The coimmunoprecipitation assay demonstrates that Sef interacts with Ras or RasG12V, respectively. We observed that Sef inhibited FGF induced, but not RasG12V mediated, signal transduction. We propose that Sef interacted with Ras in the inhibition of Ras/MAPK signaling pathway."xsd:string
http://purl.uniprot.org/citations/16859641http://purl.org/dc/terms/identifier"doi:10.1016/j.bbrc.2006.06.193"xsd:string
http://purl.uniprot.org/citations/16859641http://purl.uniprot.org/core/author"Cheng L."xsd:string
http://purl.uniprot.org/citations/16859641http://purl.uniprot.org/core/author"Li H."xsd:string
http://purl.uniprot.org/citations/16859641http://purl.uniprot.org/core/author"Li Z."xsd:string
http://purl.uniprot.org/citations/16859641http://purl.uniprot.org/core/author"Li Y."xsd:string
http://purl.uniprot.org/citations/16859641http://purl.uniprot.org/core/author"Ren Y."xsd:string
http://purl.uniprot.org/citations/16859641http://purl.uniprot.org/core/author"Wang Z."xsd:string
http://purl.uniprot.org/citations/16859641http://purl.uniprot.org/core/author"Chang Z."xsd:string
http://purl.uniprot.org/citations/16859641http://purl.uniprot.org/core/author"Rong Z."xsd:string
http://purl.uniprot.org/citations/16859641http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16859641http://purl.uniprot.org/core/name"Biochem Biophys Res Commun"xsd:string
http://purl.uniprot.org/citations/16859641http://purl.uniprot.org/core/pages"988-993"xsd:string
http://purl.uniprot.org/citations/16859641http://purl.uniprot.org/core/title"hSef co-localizes and interacts with Ras in the inhibition of Ras/MAPK signaling pathway."xsd:string
http://purl.uniprot.org/citations/16859641http://purl.uniprot.org/core/volume"347"xsd:string
http://purl.uniprot.org/citations/16859641http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16859641
http://purl.uniprot.org/citations/16859641http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/16859641
http://purl.uniprot.org/uniprot/#_B4DXM5-mappedCitation-16859641http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16859641
http://purl.uniprot.org/uniprot/#_Q8NFM7-mappedCitation-16859641http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16859641
http://purl.uniprot.org/uniprot/Q8NFM7http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/16859641
http://purl.uniprot.org/uniprot/B4DXM5http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/16859641