| http://purl.uniprot.org/citations/16860483 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16860483 | http://www.w3.org/2000/01/rdf-schema#comment | "We found that a mouse homolog of human DNA polymerase delta interacting protein 38, referred to as Mitogenin I in this paper, and mitochondrial single-stranded DNA-binding protein (mtSSB), identified as upregulated genes in the heart of mice with juvenile visceral steatosis, play a role in the regulation of mitochondrial morphology. We demonstrated that overexpression of Mitogenin I or mtSSB increased elongated or fragmented mitochondria in mouse C2C12 myoblast cells, respectively. On the other hand, the silencing of Mitogenin I or mtSSB by RNA interference led to an increase in fragmented or elongated mitochondria in the cells, respectively, suggesting that Mitogenin I and mtSSB are involved in the processes of mitochondrial fusion and fission, respectively. In addition, we showed that the silencing of Mitogenin I resulted in an increase in the number of trypan blue-positive cells and the silencing of mtSSB resulted in an enhancement of the sensitivity of the cells to apoptotic stimulation by etoposide. The present results demonstrated that these proteins play a role in cell survival."xsd:string |
| http://purl.uniprot.org/citations/16860483 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbagen.2006.05.012"xsd:string |
| http://purl.uniprot.org/citations/16860483 | http://purl.uniprot.org/core/author | "Abe R."xsd:string |
| http://purl.uniprot.org/citations/16860483 | http://purl.uniprot.org/core/author | "Shibata H."xsd:string |
| http://purl.uniprot.org/citations/16860483 | http://purl.uniprot.org/core/author | "Kita T."xsd:string |
| http://purl.uniprot.org/citations/16860483 | http://purl.uniprot.org/core/author | "Kohda A."xsd:string |
| http://purl.uniprot.org/citations/16860483 | http://purl.uniprot.org/core/author | "Higuti T."xsd:string |
| http://purl.uniprot.org/citations/16860483 | http://purl.uniprot.org/core/author | "Kuramoto Y."xsd:string |
| http://purl.uniprot.org/citations/16860483 | http://purl.uniprot.org/core/author | "Kuwajima M."xsd:string |
| http://purl.uniprot.org/citations/16860483 | http://purl.uniprot.org/core/author | "Owaki H."xsd:string |
| http://purl.uniprot.org/citations/16860483 | http://purl.uniprot.org/core/author | "Arakaki N."xsd:string |
| http://purl.uniprot.org/citations/16860483 | http://purl.uniprot.org/core/author | "Suenaga M."xsd:string |
| http://purl.uniprot.org/citations/16860483 | http://purl.uniprot.org/core/author | "Himeda T."xsd:string |
| http://purl.uniprot.org/citations/16860483 | http://purl.uniprot.org/core/author | "Nishihama T."xsd:string |
| http://purl.uniprot.org/citations/16860483 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16860483 | http://purl.uniprot.org/core/name | "Biochim Biophys Acta"xsd:string |
| http://purl.uniprot.org/citations/16860483 | http://purl.uniprot.org/core/pages | "1364-1372"xsd:string |
| http://purl.uniprot.org/citations/16860483 | http://purl.uniprot.org/core/title | "Regulation of mitochondrial morphology and cell survival by Mitogenin I and mitochondrial single-stranded DNA binding protein."xsd:string |
| http://purl.uniprot.org/citations/16860483 | http://purl.uniprot.org/core/volume | "1760"xsd:string |
| http://purl.uniprot.org/citations/16860483 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16860483 |
| http://purl.uniprot.org/citations/16860483 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16860483 |
| http://purl.uniprot.org/uniprot/Q91VA6#attribution-9F91D72FD77DE155874F3063A3A6C251 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/16860483 |
| http://purl.uniprot.org/uniprot/Q91VA6#attribution-F51F7698D65DA85F5500D644710BA688 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/16860483 |
| http://purl.uniprot.org/uniprot/Q9CYR0#attribution-9F91D72FD77DE155874F3063A3A6C251 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/16860483 |