| http://purl.uniprot.org/citations/16876997 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16876997 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16876997 | http://www.w3.org/2000/01/rdf-schema#comment | "G-protein coupled receptors (GPCR) and phosphatidylinositol phosphate kinases (PIPK) are important key switches in signal transduction pathways. A novel class of proteins was identified in the genomes of two unrelated organisms that harbor both a GPCR and a PIPK domain. Dictyostelium discoideum contains one GPCR-PIPK, which is crucial in cell-density sensing, and the genomes of Phytophthora sojae and Phytophthora ramorum each encode twelve GPCR-PIPKs. Intriguingly, these are currently the only species that have these two domains combined in one protein. Here, the structural and regulatory characteristics of GPCR-PIPKs are presented and discussed. It is hypothesized that, upon activation, GPCR-PIPKs are able to trigger heterotrimeric G-protein signaling and phosphoinositide second-messenger synthesis."xsd:string |
| http://purl.uniprot.org/citations/16876997 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.tim.2006.07.006"xsd:string |
| http://purl.uniprot.org/citations/16876997 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.tim.2006.07.006"xsd:string |
| http://purl.uniprot.org/citations/16876997 | http://purl.uniprot.org/core/author | "Bakthavatsalam D."xsd:string |
| http://purl.uniprot.org/citations/16876997 | http://purl.uniprot.org/core/author | "Bakthavatsalam D."xsd:string |
| http://purl.uniprot.org/citations/16876997 | http://purl.uniprot.org/core/author | "Govers F."xsd:string |
| http://purl.uniprot.org/citations/16876997 | http://purl.uniprot.org/core/author | "Govers F."xsd:string |
| http://purl.uniprot.org/citations/16876997 | http://purl.uniprot.org/core/author | "Noegel A.A."xsd:string |
| http://purl.uniprot.org/citations/16876997 | http://purl.uniprot.org/core/author | "Noegel A.A."xsd:string |
| http://purl.uniprot.org/citations/16876997 | http://purl.uniprot.org/core/author | "Meijer H.J."xsd:string |
| http://purl.uniprot.org/citations/16876997 | http://purl.uniprot.org/core/author | "Meijer H.J."xsd:string |
| http://purl.uniprot.org/citations/16876997 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16876997 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16876997 | http://purl.uniprot.org/core/name | "Trends Microbiol."xsd:string |
| http://purl.uniprot.org/citations/16876997 | http://purl.uniprot.org/core/name | "Trends Microbiol"xsd:string |
| http://purl.uniprot.org/citations/16876997 | http://purl.uniprot.org/core/pages | "378-382"xsd:string |
| http://purl.uniprot.org/citations/16876997 | http://purl.uniprot.org/core/pages | "378-382"xsd:string |
| http://purl.uniprot.org/citations/16876997 | http://purl.uniprot.org/core/title | "Novel phosphatidylinositol phosphate kinases with a G-protein coupled receptor signature are shared by Dictyostelium and Phytophthora."xsd:string |
| http://purl.uniprot.org/citations/16876997 | http://purl.uniprot.org/core/title | "Novel phosphatidylinositol phosphate kinases with a G-protein coupled receptor signature are shared by Dictyostelium and Phytophthora."xsd:string |
| http://purl.uniprot.org/citations/16876997 | http://purl.uniprot.org/core/volume | "14"xsd:string |
| http://purl.uniprot.org/citations/16876997 | http://purl.uniprot.org/core/volume | "14"xsd:string |
| http://purl.uniprot.org/citations/16876997 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16876997 |
| http://purl.uniprot.org/citations/16876997 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16876997 |