| http://purl.uniprot.org/citations/16877538 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16877538 | http://www.w3.org/2000/01/rdf-schema#comment | "Transcriptional activation in early spermatocytes involves hundreds of genes, many of which are required for meiosis and spermatid differentiation. A number of the meiotic-arrest genes have been identified as general regulators of transcription; however, the gene-specific transcription factors have remained elusive. To identify such factors, we purified the protein that specifically binds to the promoter of spermatid-differentiation gene Sdic and identified it as Modulo, the Drosophila homologue of nucleolin. Analysis of gene-expression patterns in the male sterile modulo mutant indicates that Modulo supports high expression of the meiotic-arrest genes and is essential for transcription of spermatid-differentiation genes. Expression of Modulo itself is under the control of meiotic-arrest genes and requires the DAZ/DAZL homologue Boule that is involved in the control of G(2)/M transition. Thus, regulatory interactions among Modulo, Boule, and the meiotic-arrest genes integrate meiosis and spermatid differentiation in the male germ line."xsd:string |
| http://purl.uniprot.org/citations/16877538 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.0605087103"xsd:string |
| http://purl.uniprot.org/citations/16877538 | http://purl.uniprot.org/core/author | "Nurminsky D.I."xsd:string |
| http://purl.uniprot.org/citations/16877538 | http://purl.uniprot.org/core/author | "Boutanaev A.M."xsd:string |
| http://purl.uniprot.org/citations/16877538 | http://purl.uniprot.org/core/author | "Mikhaylova L.M."xsd:string |
| http://purl.uniprot.org/citations/16877538 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16877538 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
| http://purl.uniprot.org/citations/16877538 | http://purl.uniprot.org/core/pages | "11975-11980"xsd:string |
| http://purl.uniprot.org/citations/16877538 | http://purl.uniprot.org/core/title | "Transcriptional regulation by Modulo integrates meiosis and spermatid differentiation in male germ line."xsd:string |
| http://purl.uniprot.org/citations/16877538 | http://purl.uniprot.org/core/volume | "103"xsd:string |
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