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http://purl.uniprot.org/citations/16892052http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16892052http://www.w3.org/2000/01/rdf-schema#comment"DNA double-strand breaks (DSB) can arise during DNA replication, or after exposure to DNA-damaging agents, and their correct repair is fundamental for cell survival and genomic stability. Here, we show that the Smc5-Smc6 complex is recruited to DSBs de novo to support their repair by homologous recombination between sister chromatids. In addition, we demonstrate that Smc5-Smc6 is necessary to suppress gross chromosomal rearrangements. Our findings show that the Smc5-Smc6 complex is essential for genome stability as it promotes repair of DSBs by error-free sister-chromatid recombination (SCR), thereby suppressing inappropriate non-sister recombination events."xsd:string
http://purl.uniprot.org/citations/16892052http://purl.org/dc/terms/identifier"doi:10.1038/ncb1466"xsd:string
http://purl.uniprot.org/citations/16892052http://purl.uniprot.org/core/author"Zhao X."xsd:string
http://purl.uniprot.org/citations/16892052http://purl.uniprot.org/core/author"Jarmuz A."xsd:string
http://purl.uniprot.org/citations/16892052http://purl.uniprot.org/core/author"Dotiwala F."xsd:string
http://purl.uniprot.org/citations/16892052http://purl.uniprot.org/core/author"Haber J.E."xsd:string
http://purl.uniprot.org/citations/16892052http://purl.uniprot.org/core/author"Aguilera A."xsd:string
http://purl.uniprot.org/citations/16892052http://purl.uniprot.org/core/author"Cortes-Ledesma F."xsd:string
http://purl.uniprot.org/citations/16892052http://purl.uniprot.org/core/author"Hwang J.Y."xsd:string
http://purl.uniprot.org/citations/16892052http://purl.uniprot.org/core/author"Ira G."xsd:string
http://purl.uniprot.org/citations/16892052http://purl.uniprot.org/core/author"Myung K."xsd:string
http://purl.uniprot.org/citations/16892052http://purl.uniprot.org/core/author"Clemente-Blanco A."xsd:string
http://purl.uniprot.org/citations/16892052http://purl.uniprot.org/core/author"Aragon L."xsd:string
http://purl.uniprot.org/citations/16892052http://purl.uniprot.org/core/author"Machin F."xsd:string
http://purl.uniprot.org/citations/16892052http://purl.uniprot.org/core/author"Torres-Rosell J."xsd:string
http://purl.uniprot.org/citations/16892052http://purl.uniprot.org/core/author"Uhle S."xsd:string
http://purl.uniprot.org/citations/16892052http://purl.uniprot.org/core/author"Papusha A."xsd:string
http://purl.uniprot.org/citations/16892052http://purl.uniprot.org/core/author"Ullal P."xsd:string
http://purl.uniprot.org/citations/16892052http://purl.uniprot.org/core/author"Cordon-Preciado V."xsd:string
http://purl.uniprot.org/citations/16892052http://purl.uniprot.org/core/author"Farmer S."xsd:string
http://purl.uniprot.org/citations/16892052http://purl.uniprot.org/core/author"Bressan D."xsd:string
http://purl.uniprot.org/citations/16892052http://purl.uniprot.org/core/author"De Piccoli G."xsd:string
http://purl.uniprot.org/citations/16892052http://purl.uniprot.org/core/author"Ceschia A."xsd:string
http://purl.uniprot.org/citations/16892052http://purl.uniprot.org/core/author"Leitao B."xsd:string