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http://purl.uniprot.org/citations/16908179http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16908179http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16908179http://www.w3.org/2000/01/rdf-schema#comment"Knowledge about the biological functions and clinical implications of interleukin (IL)-20, a recently discovered cytokine in the IL-10 family, is still incomplete. Our aim was to determine the distribution of IL-20 expression and to delineate the cell types that express IL-20 in healthy and neoplastic tissue, because this information will significantly affect the exploration of its pathophysiological roles. We used tissue microarray technology and an immunohistochemical survey using an anti-IL-20 monoclonal antibody to examine IL-20 expression in 36 non-neoplastic and 14 neoplastic tissues. IL-20 protein was positively stained in 30 non-neoplastic tissue types and five major cell types: epithelial cells, myoepithelial cells, endothelial cells, macrophages, and skeletal muscle cells. We also found that several types of tumor cells stained positive for IL-20, especially in squamous cell carcinoma of the skin, tongue, esophagus, and lung. Our data provide valuable references for further investigation of the biological functions and clinical implications of IL-20 in humans."xsd:string
http://purl.uniprot.org/citations/16908179http://purl.org/dc/terms/identifier"doi:10.1016/j.cyto.2006.07.006"xsd:string
http://purl.uniprot.org/citations/16908179http://purl.org/dc/terms/identifier"doi:10.1016/j.cyto.2006.07.006"xsd:string
http://purl.uniprot.org/citations/16908179http://purl.uniprot.org/core/author"Ho C.L."xsd:string
http://purl.uniprot.org/citations/16908179http://purl.uniprot.org/core/author"Ho C.L."xsd:string
http://purl.uniprot.org/citations/16908179http://purl.uniprot.org/core/author"Chang L.Y."xsd:string
http://purl.uniprot.org/citations/16908179http://purl.uniprot.org/core/author"Chang L.Y."xsd:string
http://purl.uniprot.org/citations/16908179http://purl.uniprot.org/core/author"Chang M.S."xsd:string
http://purl.uniprot.org/citations/16908179http://purl.uniprot.org/core/author"Chang M.S."xsd:string
http://purl.uniprot.org/citations/16908179http://purl.uniprot.org/core/author"Lee Y.L."xsd:string
http://purl.uniprot.org/citations/16908179http://purl.uniprot.org/core/author"Lee Y.L."xsd:string
http://purl.uniprot.org/citations/16908179http://purl.uniprot.org/core/author"Chuang S.S."xsd:string
http://purl.uniprot.org/citations/16908179http://purl.uniprot.org/core/author"Chuang S.S."xsd:string
http://purl.uniprot.org/citations/16908179http://purl.uniprot.org/core/author"Hsing C.H."xsd:string
http://purl.uniprot.org/citations/16908179http://purl.uniprot.org/core/author"Hsing C.H."xsd:string
http://purl.uniprot.org/citations/16908179http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16908179http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16908179http://purl.uniprot.org/core/name"Cytokine"xsd:string
http://purl.uniprot.org/citations/16908179http://purl.uniprot.org/core/name"Cytokine"xsd:string
http://purl.uniprot.org/citations/16908179http://purl.uniprot.org/core/pages"44-52"xsd:string
http://purl.uniprot.org/citations/16908179http://purl.uniprot.org/core/pages"44-52"xsd:string
http://purl.uniprot.org/citations/16908179http://purl.uniprot.org/core/title"Tissue microarray analysis of interleukin-20 expression."xsd:string
http://purl.uniprot.org/citations/16908179http://purl.uniprot.org/core/title"Tissue microarray analysis of interleukin-20 expression."xsd:string