http://purl.uniprot.org/citations/16919269 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16919269 | http://www.w3.org/2000/01/rdf-schema#comment | "Highly conserved non-coding DNA regions (HCNR) occur frequently in vertebrate genomes, but their functional roles remain unclear. Here, we provide evidence that a large portion of HCNRs are enriched for binding sites for Sox, POU and Homeodomain transcription factors, and such HCNRs can act as cis-regulatory regions active in neural stem cells. Strikingly, these HCNRs are linked to several hundreds of genes expressed in the developing CNS and they may exert locus-wide regulatory effects on multiple genes flanking their genomic location. Moreover, these data imply a unifying transcriptional logic for a large set of CNS-expressed genes in which Sox and POU proteins act as generic promoters of transcription while Homeodomain proteins control the spatial expression of genes through active repression."xsd:string |
http://purl.uniprot.org/citations/16919269 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.yexcr.2006.06.017"xsd:string |
http://purl.uniprot.org/citations/16919269 | http://purl.uniprot.org/core/author | "Lenhard B."xsd:string |
http://purl.uniprot.org/citations/16919269 | http://purl.uniprot.org/core/author | "Sandelin A."xsd:string |
http://purl.uniprot.org/citations/16919269 | http://purl.uniprot.org/core/author | "Andersson E."xsd:string |
http://purl.uniprot.org/citations/16919269 | http://purl.uniprot.org/core/author | "Ericson J."xsd:string |
http://purl.uniprot.org/citations/16919269 | http://purl.uniprot.org/core/author | "Muhr J."xsd:string |
http://purl.uniprot.org/citations/16919269 | http://purl.uniprot.org/core/author | "Karlen M."xsd:string |
http://purl.uniprot.org/citations/16919269 | http://purl.uniprot.org/core/author | "Bailey P.J."xsd:string |
http://purl.uniprot.org/citations/16919269 | http://purl.uniprot.org/core/author | "Klos J.M."xsd:string |
http://purl.uniprot.org/citations/16919269 | http://purl.uniprot.org/core/author | "Kallstrom M."xsd:string |
http://purl.uniprot.org/citations/16919269 | http://purl.uniprot.org/core/author | "Ponjavic J."xsd:string |
http://purl.uniprot.org/citations/16919269 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
http://purl.uniprot.org/citations/16919269 | http://purl.uniprot.org/core/name | "Exp Cell Res"xsd:string |
http://purl.uniprot.org/citations/16919269 | http://purl.uniprot.org/core/pages | "3108-3119"xsd:string |
http://purl.uniprot.org/citations/16919269 | http://purl.uniprot.org/core/title | "A global genomic transcriptional code associated with CNS-expressed genes."xsd:string |
http://purl.uniprot.org/citations/16919269 | http://purl.uniprot.org/core/volume | "312"xsd:string |
http://purl.uniprot.org/citations/16919269 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16919269 |
http://purl.uniprot.org/citations/16919269 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16919269 |
http://purl.uniprot.org/uniprot/#_A0A0A6YVW7-mappedCitation-16919269 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16919269 |
http://purl.uniprot.org/uniprot/#_A0A0A6YVX7-mappedCitation-16919269 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16919269 |
http://purl.uniprot.org/uniprot/#_A0A0A6YVY5-mappedCitation-16919269 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16919269 |
http://purl.uniprot.org/uniprot/#_A0A0A6YW74-mappedCitation-16919269 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16919269 |
http://purl.uniprot.org/uniprot/#_A0A0A6YW90-mappedCitation-16919269 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16919269 |