| http://purl.uniprot.org/citations/16920206 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
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| http://purl.uniprot.org/citations/16920206 | http://www.w3.org/2000/01/rdf-schema#comment | "Rab11a is a member of the Rab11 small GTPase family, and plays an important role in plasma membrane recycling. Rab11-Family Interacting Protein 1 (Rab11-FIP1) binds to Rab11 through a carboxyl-terminal amphipathic alpha helix. We have identified eight alternatively spliced Rab11-FIP1 gene transcripts from human chromosome 8. Among them, Rab11-FIP1A-D have carboxyl terminal Rab11 binding domains, while Rab11-FIP1E-H do not contain the Rab11 binding domain. While Rab11-FIP1B and F gene transcripts are ubiquitous, other Rab11-FIP1 transcripts demonstrate more limited patterns of expression in human tissue cDNAs. EGFP-Rab11-FIP1A-D proteins over-expressed in HeLa cells targeted to Rab11a-containing membranes, while EGFP-Rab11-FIP1E/F and H proteins did not localize with recycling system membranes. However, transferrin trafficking was not significantly altered in HeLa cells over-expressing expressing any of the EGFP-Rab11-FIP1 proteins. Rabbit polyclonal antibodies specific for Rab11-FIP1B and Rab11-FIP1C/RCP demonstrated that Rab11-FIP1B and Rab11-FIP1C/RCP are expressed endogenously. Strikingly, endogenous staining for Rab11-FIP1C/RCP only partially co-localized with EGFP-Rab11-FIP1A, EGFP-Rab11-FIP1B, and EGFP-Rab11a in the perinuclear region, indicating that Rab11-FIP1C/RCP resides in a differentiable subcellular compartment within the plasma membrane recycling system compared with Rab11-FIP1A and Rab11-FIP1B. These data suggest that Rab11-FIP1 proteins may play coordinated roles in regulating plasma membrane recycling with regional specificity within the Rab11a-containing recycling system."xsd:string |
| http://purl.uniprot.org/citations/16920206 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbaexp.2006.06.001"xsd:string |
| http://purl.uniprot.org/citations/16920206 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbaexp.2006.06.001"xsd:string |
| http://purl.uniprot.org/citations/16920206 | http://purl.uniprot.org/core/author | "Jin M."xsd:string |
| http://purl.uniprot.org/citations/16920206 | http://purl.uniprot.org/core/author | "Jin M."xsd:string |
| http://purl.uniprot.org/citations/16920206 | http://purl.uniprot.org/core/author | "Goldenring J.R."xsd:string |
| http://purl.uniprot.org/citations/16920206 | http://purl.uniprot.org/core/author | "Goldenring J.R."xsd:string |
| http://purl.uniprot.org/citations/16920206 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16920206 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16920206 | http://purl.uniprot.org/core/name | "Biochim. Biophys. Acta"xsd:string |
| http://purl.uniprot.org/citations/16920206 | http://purl.uniprot.org/core/name | "Biochim. Biophys. Acta"xsd:string |
| http://purl.uniprot.org/citations/16920206 | http://purl.uniprot.org/core/pages | "281-295"xsd:string |
| http://purl.uniprot.org/citations/16920206 | http://purl.uniprot.org/core/pages | "281-295"xsd:string |
| http://purl.uniprot.org/citations/16920206 | http://purl.uniprot.org/core/title | "The Rab11-FIP1/RCP gene codes for multiple protein transcripts related to the plasma membrane recycling system."xsd:string |
| http://purl.uniprot.org/citations/16920206 | http://purl.uniprot.org/core/title | "The Rab11-FIP1/RCP gene codes for multiple protein transcripts related to the plasma membrane recycling system."xsd:string |
| http://purl.uniprot.org/citations/16920206 | http://purl.uniprot.org/core/volume | "1759"xsd:string |
| http://purl.uniprot.org/citations/16920206 | http://purl.uniprot.org/core/volume | "1759"xsd:string |
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| http://purl.uniprot.org/citations/16920206 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16920206 |
| http://purl.uniprot.org/uniprot/Q67C35 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/16920206 |
| http://purl.uniprot.org/uniprot/Q6WKZ4 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/16920206 |