| http://purl.uniprot.org/citations/16964252 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16964252 | http://www.w3.org/2000/01/rdf-schema#comment | "Cajal-Retzius cells are critical in the development of the cerebral cortex, but little is known about the mechanisms controlling their development. Three focal sources of Cajal-Retzius cells have been identified in mice-the cortical hem, the ventral pallium and the septum-from where they migrate tangentially to populate the cortical surface. Using a variety of tissue culture assays and in vivo manipulations, we demonstrate that the tangential migration of cortical hem-derived Cajal-Retzius cells is controlled by the meninges. We show that the meningeal membranes are a necessary and sufficient substrate for the tangential migration of Cajal-Retzius cells. We also show that the chemokine CXCL12 secreted by the meninges enhances the dispersion of Cajal-Retzius cells along the cortical surface, while retaining them within the marginal zone in a CXCR4-dependent manner. Thus, the meningeal membranes are fundamental in the development of Cajal-Retzius cells and, hence, in the normal development of the cerebral cortex."xsd:string |
| http://purl.uniprot.org/citations/16964252 | http://purl.org/dc/terms/identifier | "doi:10.1038/nn1764"xsd:string |
| http://purl.uniprot.org/citations/16964252 | http://purl.uniprot.org/core/author | "Marin O."xsd:string |
| http://purl.uniprot.org/citations/16964252 | http://purl.uniprot.org/core/author | "Borrell V."xsd:string |
| http://purl.uniprot.org/citations/16964252 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16964252 | http://purl.uniprot.org/core/name | "Nat Neurosci"xsd:string |
| http://purl.uniprot.org/citations/16964252 | http://purl.uniprot.org/core/pages | "1284-1293"xsd:string |
| http://purl.uniprot.org/citations/16964252 | http://purl.uniprot.org/core/title | "Meninges control tangential migration of hem-derived Cajal-Retzius cells via CXCL12/CXCR4 signaling."xsd:string |
| http://purl.uniprot.org/citations/16964252 | http://purl.uniprot.org/core/volume | "9"xsd:string |
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