http://purl.uniprot.org/citations/16964398 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16964398 | http://www.w3.org/2000/01/rdf-schema#comment | "EG-1 is significantly elevated in breast, colorectal, and prostate cancers. Overexpression of EG-1 stimulates cellular proliferation, and targeted inhibition blocks mouse xenograft tumor growth. To further clarify the function of EG-1, we investigated its role in c-Src activation. We observed that EG-1 overexpression results in activation of c-Src, but found no evidence that EG-1 is a direct Src substrate. EG-1 also binds to other members of the Src family. Furthermore, EG-1 shows interaction with multiple other SH3- and WW-containing molecules involved in various signaling pathways. These observations suggest that EG-1 may be involved in signaling pathways including c-Src activation."xsd:string |
http://purl.uniprot.org/citations/16964398 | http://purl.uniprot.org/core/author | "Lu M."xsd:string |
http://purl.uniprot.org/citations/16964398 | http://purl.uniprot.org/core/author | "Zhang L."xsd:string |
http://purl.uniprot.org/citations/16964398 | http://purl.uniprot.org/core/author | "Norris A.J."xsd:string |
http://purl.uniprot.org/citations/16964398 | http://purl.uniprot.org/core/author | "Brooks M.N."xsd:string |
http://purl.uniprot.org/citations/16964398 | http://purl.uniprot.org/core/author | "Sartippour M.R."xsd:string |
http://purl.uniprot.org/citations/16964398 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
http://purl.uniprot.org/citations/16964398 | http://purl.uniprot.org/core/name | "Int J Oncol"xsd:string |
http://purl.uniprot.org/citations/16964398 | http://purl.uniprot.org/core/pages | "1013-1018"xsd:string |
http://purl.uniprot.org/citations/16964398 | http://purl.uniprot.org/core/title | "EG-1 interacts with c-Src and activates its signaling pathway."xsd:string |
http://purl.uniprot.org/citations/16964398 | http://purl.uniprot.org/core/volume | "29"xsd:string |
http://purl.uniprot.org/citations/16964398 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16964398 |
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