http://purl.uniprot.org/citations/16979624 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16979624 | http://www.w3.org/2000/01/rdf-schema#comment | "The cadherin superfamily protein Fat1 is known to interact with the EVH1 domain of mammalian Ena/VASP. Here we demonstrate that: (i) the scaffolding proteins Homer-3 and Homer-1 also interact with the EVH1 binding site of hFat1 in vitro, and (ii) binding of Homer-3 and Mena to hFat1 is mutually competitive. Endogenous Fat1 binds to immobilised Homer-3 and endogenous Homer-3 binds to immobilised Fat1. Both, endogenous and over-expressed Fat1 exhibit co-localisation with Homer-3 in cellular protrusions and at the plasma membrane of HeLa cells. As Homer proteins and Fat1 have been both linked to psychic disorders, their interaction may be of patho-physiological importance."xsd:string |
http://purl.uniprot.org/citations/16979624 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2006.08.079"xsd:string |
http://purl.uniprot.org/citations/16979624 | http://purl.uniprot.org/core/author | "Muller K."xsd:string |
http://purl.uniprot.org/citations/16979624 | http://purl.uniprot.org/core/author | "Hofer H.W."xsd:string |
http://purl.uniprot.org/citations/16979624 | http://purl.uniprot.org/core/author | "Schreiner D."xsd:string |
http://purl.uniprot.org/citations/16979624 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
http://purl.uniprot.org/citations/16979624 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
http://purl.uniprot.org/citations/16979624 | http://purl.uniprot.org/core/pages | "5295-5300"xsd:string |
http://purl.uniprot.org/citations/16979624 | http://purl.uniprot.org/core/title | "The intracellular domain of the human protocadherin hFat1 interacts with Homer signalling scaffolding proteins."xsd:string |
http://purl.uniprot.org/citations/16979624 | http://purl.uniprot.org/core/volume | "580"xsd:string |
http://purl.uniprot.org/citations/16979624 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16979624 |
http://purl.uniprot.org/citations/16979624 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16979624 |
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http://purl.uniprot.org/uniprot/#_Q99JP6-mappedCitation-16979624 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16979624 |
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http://purl.uniprot.org/uniprot/#_Q9UEJ6-mappedCitation-16979624 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16979624 |