http://purl.uniprot.org/citations/16980967 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16980967 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16980967 | http://www.w3.org/2000/01/rdf-schema#comment | "Synaptic cell adhesion molecules (CAMs) regulate synapse formation through their trans-synaptic and heterophilic adhesion. Here we show that postsynaptic netrin-G ligand (NGL) CAMs associate with netrin-G CAMs in an isoform-specific manner and, through their cytosolic tail, with the abundant postsynaptic scaffold postsynaptic density-95 (PSD-95). Overexpression of NGL-2 in cultured rat neurons increased the number of PSD-95-positive dendritic protrusions. NGL-2 located on heterologous cells or beads induced functional presynaptic differentiation in contacting neurites. Direct aggregation of NGL-2 on the surface membrane of dendrites induced the clustering of excitatory postsynaptic proteins. Competitive inhibition by soluble NGL-2 reduced the number of excitatory synapses. NGL-2 knockdown reduced excitatory, but not inhibitory, synapse numbers and currents. These results suggest that NGL regulates the formation of excitatory synapses."xsd:string |
http://purl.uniprot.org/citations/16980967 | http://purl.org/dc/terms/identifier | "doi:10.1038/nn1763"xsd:string |
http://purl.uniprot.org/citations/16980967 | http://purl.org/dc/terms/identifier | "doi:10.1038/nn1763"xsd:string |
http://purl.uniprot.org/citations/16980967 | http://purl.uniprot.org/core/author | "Chung H.S."xsd:string |
http://purl.uniprot.org/citations/16980967 | http://purl.uniprot.org/core/author | "Chung H.S."xsd:string |
http://purl.uniprot.org/citations/16980967 | http://purl.uniprot.org/core/author | "Kim E."xsd:string |
http://purl.uniprot.org/citations/16980967 | http://purl.uniprot.org/core/author | "Kim E."xsd:string |
http://purl.uniprot.org/citations/16980967 | http://purl.uniprot.org/core/author | "Kim K."xsd:string |
http://purl.uniprot.org/citations/16980967 | http://purl.uniprot.org/core/author | "Kim K."xsd:string |
http://purl.uniprot.org/citations/16980967 | http://purl.uniprot.org/core/author | "Kim H."xsd:string |
http://purl.uniprot.org/citations/16980967 | http://purl.uniprot.org/core/author | "Kim H."xsd:string |
http://purl.uniprot.org/citations/16980967 | http://purl.uniprot.org/core/author | "Kim S."xsd:string |
http://purl.uniprot.org/citations/16980967 | http://purl.uniprot.org/core/author | "Kim S."xsd:string |
http://purl.uniprot.org/citations/16980967 | http://purl.uniprot.org/core/author | "Lee H.W."xsd:string |
http://purl.uniprot.org/citations/16980967 | http://purl.uniprot.org/core/author | "Lee H.W."xsd:string |
http://purl.uniprot.org/citations/16980967 | http://purl.uniprot.org/core/author | "Woo J."xsd:string |
http://purl.uniprot.org/citations/16980967 | http://purl.uniprot.org/core/author | "Woo J."xsd:string |
http://purl.uniprot.org/citations/16980967 | http://purl.uniprot.org/core/author | "Weinberg R.J."xsd:string |
http://purl.uniprot.org/citations/16980967 | http://purl.uniprot.org/core/author | "Weinberg R.J."xsd:string |
http://purl.uniprot.org/citations/16980967 | http://purl.uniprot.org/core/author | "Burette A."xsd:string |
http://purl.uniprot.org/citations/16980967 | http://purl.uniprot.org/core/author | "Burette A."xsd:string |
http://purl.uniprot.org/citations/16980967 | http://purl.uniprot.org/core/author | "Kwon S.-K."xsd:string |
http://purl.uniprot.org/citations/16980967 | http://purl.uniprot.org/core/author | "Kwon S.-K."xsd:string |