| http://purl.uniprot.org/citations/16996037 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16996037 | http://www.w3.org/2000/01/rdf-schema#comment | "The heptapeptide Semax (Met-Glu-His-Phe-Pro-Gly-Pro) is an analog of the adrenocorticotropin fragment (4-10) which after intranasal application has profound effects on learning and exerts marked neuroprotective activities. Here, we found that a single application of Semax (50 microg/kg body weight) results in a maximal 1.4-fold increase of BDNF protein levels accompanying with 1.6-fold increase of trkB tyrosine phosporylation levels, and a 3-fold and a 2-fold increase of exon III BDNF and trkB mRNA levels, respectively, in the rat hippocampus. Semax-treated animals showed a distinct increase in the number of conditioned avoidance reactions. We suggest that Semax affects cognitive brain functions by modulating the expression and the activation of the hippocampal BDNF/trkB system."xsd:string |
| http://purl.uniprot.org/citations/16996037 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.brainres.2006.07.108"xsd:string |
| http://purl.uniprot.org/citations/16996037 | http://purl.uniprot.org/core/author | "Kamensky A.A."xsd:string |
| http://purl.uniprot.org/citations/16996037 | http://purl.uniprot.org/core/author | "Levitskaya N.G."xsd:string |
| http://purl.uniprot.org/citations/16996037 | http://purl.uniprot.org/core/author | "Engele J."xsd:string |
| http://purl.uniprot.org/citations/16996037 | http://purl.uniprot.org/core/author | "Rozyczka J."xsd:string |
| http://purl.uniprot.org/citations/16996037 | http://purl.uniprot.org/core/author | "Grivennikov I.A."xsd:string |
| http://purl.uniprot.org/citations/16996037 | http://purl.uniprot.org/core/author | "Dolotov O.V."xsd:string |
| http://purl.uniprot.org/citations/16996037 | http://purl.uniprot.org/core/author | "Inozemtseva L.S."xsd:string |
| http://purl.uniprot.org/citations/16996037 | http://purl.uniprot.org/core/author | "Novosadova E.V."xsd:string |
| http://purl.uniprot.org/citations/16996037 | http://purl.uniprot.org/core/author | "Seredenina T.S."xsd:string |
| http://purl.uniprot.org/citations/16996037 | http://purl.uniprot.org/core/author | "Alfeeva L.Y."xsd:string |
| http://purl.uniprot.org/citations/16996037 | http://purl.uniprot.org/core/author | "Andreeva L.A."xsd:string |
| http://purl.uniprot.org/citations/16996037 | http://purl.uniprot.org/core/author | "Dubynina E.V."xsd:string |
| http://purl.uniprot.org/citations/16996037 | http://purl.uniprot.org/core/author | "Karpenko E.A."xsd:string |
| http://purl.uniprot.org/citations/16996037 | http://purl.uniprot.org/core/author | "Myasoedov N.F."xsd:string |
| http://purl.uniprot.org/citations/16996037 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16996037 | http://purl.uniprot.org/core/name | "Brain Res"xsd:string |
| http://purl.uniprot.org/citations/16996037 | http://purl.uniprot.org/core/pages | "54-60"xsd:string |
| http://purl.uniprot.org/citations/16996037 | http://purl.uniprot.org/core/title | "Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus."xsd:string |
| http://purl.uniprot.org/citations/16996037 | http://purl.uniprot.org/core/volume | "1117"xsd:string |
| http://purl.uniprot.org/citations/16996037 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16996037 |
| http://purl.uniprot.org/citations/16996037 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16996037 |
| http://purl.uniprot.org/uniprot/#_A0A0G2K624-mappedCitation-16996037 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16996037 |