| http://purl.uniprot.org/citations/17008357 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17008357 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17008357 | http://www.w3.org/2000/01/rdf-schema#comment | "Secretin is a peptide hormone released from the duodenum to stimulate the secretion of digestive juice by the pancreas. Secretin also functions as a neuropeptide hormone in the brain, and exogenous administration has been reported to alleviate symptoms in some patients with autism. We have generated secretin receptor-deficient mice to explore the relationship between secretin signaling in the brain and behavioral phenotypes. Secretin receptor-deficient mice are overtly normal and fertile; however, synaptic plasticity in the hippocampus is impaired and there are slightly fewer dendritic spines in the CA1 hippocampal pyramidal cells. Furthermore, secretin receptor-deficient mice show abnormal social and cognitive behaviors. These findings suggest that the secretin receptor system has an important role in the central nervous system relating to social behavior."xsd:string |
| http://purl.uniprot.org/citations/17008357 | http://purl.org/dc/terms/identifier | "doi:10.1093/hmg/ddl402"xsd:string |
| http://purl.uniprot.org/citations/17008357 | http://purl.org/dc/terms/identifier | "doi:10.1093/hmg/ddl402"xsd:string |
| http://purl.uniprot.org/citations/17008357 | http://purl.uniprot.org/core/author | "Ito M."xsd:string |
| http://purl.uniprot.org/citations/17008357 | http://purl.uniprot.org/core/author | "Ito M."xsd:string |
| http://purl.uniprot.org/citations/17008357 | http://purl.uniprot.org/core/author | "Nelson D.L."xsd:string |
| http://purl.uniprot.org/citations/17008357 | http://purl.uniprot.org/core/author | "Nelson D.L."xsd:string |
| http://purl.uniprot.org/citations/17008357 | http://purl.uniprot.org/core/author | "Yamagata T."xsd:string |
| http://purl.uniprot.org/citations/17008357 | http://purl.uniprot.org/core/author | "Yamagata T."xsd:string |
| http://purl.uniprot.org/citations/17008357 | http://purl.uniprot.org/core/author | "Bradley A."xsd:string |
| http://purl.uniprot.org/citations/17008357 | http://purl.uniprot.org/core/author | "Bradley A."xsd:string |
| http://purl.uniprot.org/citations/17008357 | http://purl.uniprot.org/core/author | "Sweatt J.D."xsd:string |
| http://purl.uniprot.org/citations/17008357 | http://purl.uniprot.org/core/author | "Sweatt J.D."xsd:string |
| http://purl.uniprot.org/citations/17008357 | http://purl.uniprot.org/core/author | "Weeber E.J."xsd:string |
| http://purl.uniprot.org/citations/17008357 | http://purl.uniprot.org/core/author | "Weeber E.J."xsd:string |
| http://purl.uniprot.org/citations/17008357 | http://purl.uniprot.org/core/author | "Paylor R."xsd:string |
| http://purl.uniprot.org/citations/17008357 | http://purl.uniprot.org/core/author | "Paylor R."xsd:string |
| http://purl.uniprot.org/citations/17008357 | http://purl.uniprot.org/core/author | "Armstrong D.L."xsd:string |
| http://purl.uniprot.org/citations/17008357 | http://purl.uniprot.org/core/author | "Armstrong D.L."xsd:string |
| http://purl.uniprot.org/citations/17008357 | http://purl.uniprot.org/core/author | "Momoi M.Y."xsd:string |
| http://purl.uniprot.org/citations/17008357 | http://purl.uniprot.org/core/author | "Momoi M.Y."xsd:string |
| http://purl.uniprot.org/citations/17008357 | http://purl.uniprot.org/core/author | "Nishijima I."xsd:string |
| http://purl.uniprot.org/citations/17008357 | http://purl.uniprot.org/core/author | "Nishijima I."xsd:string |