| http://purl.uniprot.org/citations/1701694 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1701694 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1701694 | http://www.w3.org/2000/01/rdf-schema#comment | "Plasma membrane forms of guanylyl cyclase have been shown to function as natriuretic peptide receptors. We describe a new clone (GC-C) encoding a guanylyl cyclase receptor for heat-stable enterotoxin. GC-C encodes a protein containing an extracellular amino acid sequence divergent from that of previously cloned guanylyl cyclases; however, the protein retains the intracellular protein kinase-like and cyclase catalytic domains. Expression of GC-C in COS-7 cells results in high guanylyl cyclase activity. In addition, heat-stable enterotoxin from E. coli, but not natriuretic peptides, causes marked elevations of cyclic GMP and is specifically bound by cells transfected with GC-C. The enterotoxin fails to elevate cyclic GMP in nontransfected cells or in cells transfected with the natriuretic peptide/guanylyl cyclase receptors. These results show that a heat-stable enterotoxin receptor responsible for acute diarrhea is a plasma membrane form of guanylyl cyclase."xsd:string |
| http://purl.uniprot.org/citations/1701694 | http://purl.org/dc/terms/identifier | "doi:10.1016/0092-8674(90)90497-3"xsd:string |
| http://purl.uniprot.org/citations/1701694 | http://purl.org/dc/terms/identifier | "doi:10.1016/0092-8674(90)90497-3"xsd:string |
| http://purl.uniprot.org/citations/1701694 | http://purl.uniprot.org/core/author | "Schulz S."xsd:string |
| http://purl.uniprot.org/citations/1701694 | http://purl.uniprot.org/core/author | "Schulz S."xsd:string |
| http://purl.uniprot.org/citations/1701694 | http://purl.uniprot.org/core/author | "Garbers D.L."xsd:string |
| http://purl.uniprot.org/citations/1701694 | http://purl.uniprot.org/core/author | "Garbers D.L."xsd:string |
| http://purl.uniprot.org/citations/1701694 | http://purl.uniprot.org/core/author | "Yuen P.S.T."xsd:string |
| http://purl.uniprot.org/citations/1701694 | http://purl.uniprot.org/core/author | "Yuen P.S.T."xsd:string |
| http://purl.uniprot.org/citations/1701694 | http://purl.uniprot.org/core/author | "Green C.K."xsd:string |
| http://purl.uniprot.org/citations/1701694 | http://purl.uniprot.org/core/author | "Green C.K."xsd:string |
| http://purl.uniprot.org/citations/1701694 | http://purl.uniprot.org/core/date | "1990"xsd:gYear |
| http://purl.uniprot.org/citations/1701694 | http://purl.uniprot.org/core/date | "1990"xsd:gYear |
| http://purl.uniprot.org/citations/1701694 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/1701694 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/1701694 | http://purl.uniprot.org/core/pages | "941-948"xsd:string |
| http://purl.uniprot.org/citations/1701694 | http://purl.uniprot.org/core/pages | "941-948"xsd:string |
| http://purl.uniprot.org/citations/1701694 | http://purl.uniprot.org/core/title | "Guanylyl cyclase is a heat-stable enterotoxin receptor."xsd:string |
| http://purl.uniprot.org/citations/1701694 | http://purl.uniprot.org/core/title | "Guanylyl cyclase is a heat-stable enterotoxin receptor."xsd:string |
| http://purl.uniprot.org/citations/1701694 | http://purl.uniprot.org/core/volume | "63"xsd:string |
| http://purl.uniprot.org/citations/1701694 | http://purl.uniprot.org/core/volume | "63"xsd:string |
| http://purl.uniprot.org/citations/1701694 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1701694 |
| http://purl.uniprot.org/citations/1701694 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1701694 |