http://purl.uniprot.org/citations/17027647 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17027647 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17027647 | http://www.w3.org/2000/01/rdf-schema#comment | "The death receptor 5 (DR-5), a receptor for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), is critical for TRAIL-mediated apoptosis in various tumor cells. The ESE-3, a member of Ets transcription factors, regulates the expression of a variety of cellular genes by binding to purine-rich GGAA/T core sequence in cooperation with other transcription factors and co-factors. In this study, we demonstrate for the first time that ESE-3 regulates DR-5 expression through Ets binding sequences on the DR-5 promoter. Using a combination of the electrophoretic mobility shift assay and the luciferase reporter assay, we identified putative Ets sites responsible for ESE-3 transcriptional activity on the DR-5 promoter. In addition, we show the possible involvement of co-factors CBP and p300 in ESE-3-mediated DR-5 up-regulation."xsd:string |
http://purl.uniprot.org/citations/17027647 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2006.09.102"xsd:string |
http://purl.uniprot.org/citations/17027647 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2006.09.102"xsd:string |
http://purl.uniprot.org/citations/17027647 | http://purl.uniprot.org/core/author | "Cho J.-Y."xsd:string |
http://purl.uniprot.org/citations/17027647 | http://purl.uniprot.org/core/author | "Cho J.-Y."xsd:string |
http://purl.uniprot.org/citations/17027647 | http://purl.uniprot.org/core/author | "Lim J.H."xsd:string |
http://purl.uniprot.org/citations/17027647 | http://purl.uniprot.org/core/author | "Lim J.H."xsd:string |
http://purl.uniprot.org/citations/17027647 | http://purl.uniprot.org/core/author | "Park Y.B."xsd:string |
http://purl.uniprot.org/citations/17027647 | http://purl.uniprot.org/core/author | "Park Y.B."xsd:string |
http://purl.uniprot.org/citations/17027647 | http://purl.uniprot.org/core/author | "Park J.-W."xsd:string |
http://purl.uniprot.org/citations/17027647 | http://purl.uniprot.org/core/author | "Park J.-W."xsd:string |
http://purl.uniprot.org/citations/17027647 | http://purl.uniprot.org/core/author | "Kwon T.K."xsd:string |
http://purl.uniprot.org/citations/17027647 | http://purl.uniprot.org/core/author | "Kwon T.K."xsd:string |
http://purl.uniprot.org/citations/17027647 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
http://purl.uniprot.org/citations/17027647 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
http://purl.uniprot.org/citations/17027647 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
http://purl.uniprot.org/citations/17027647 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
http://purl.uniprot.org/citations/17027647 | http://purl.uniprot.org/core/pages | "736-741"xsd:string |
http://purl.uniprot.org/citations/17027647 | http://purl.uniprot.org/core/pages | "736-741"xsd:string |
http://purl.uniprot.org/citations/17027647 | http://purl.uniprot.org/core/title | "ESE-3 transcription factor is involved in the expression of death receptor (DR)-5 through putative Ets sites."xsd:string |
http://purl.uniprot.org/citations/17027647 | http://purl.uniprot.org/core/title | "ESE-3 transcription factor is involved in the expression of death receptor (DR)-5 through putative Ets sites."xsd:string |
http://purl.uniprot.org/citations/17027647 | http://purl.uniprot.org/core/volume | "350"xsd:string |
http://purl.uniprot.org/citations/17027647 | http://purl.uniprot.org/core/volume | "350"xsd:string |