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http://purl.uniprot.org/citations/17027647http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17027647http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17027647http://www.w3.org/2000/01/rdf-schema#comment"The death receptor 5 (DR-5), a receptor for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), is critical for TRAIL-mediated apoptosis in various tumor cells. The ESE-3, a member of Ets transcription factors, regulates the expression of a variety of cellular genes by binding to purine-rich GGAA/T core sequence in cooperation with other transcription factors and co-factors. In this study, we demonstrate for the first time that ESE-3 regulates DR-5 expression through Ets binding sequences on the DR-5 promoter. Using a combination of the electrophoretic mobility shift assay and the luciferase reporter assay, we identified putative Ets sites responsible for ESE-3 transcriptional activity on the DR-5 promoter. In addition, we show the possible involvement of co-factors CBP and p300 in ESE-3-mediated DR-5 up-regulation."xsd:string
http://purl.uniprot.org/citations/17027647http://purl.org/dc/terms/identifier"doi:10.1016/j.bbrc.2006.09.102"xsd:string
http://purl.uniprot.org/citations/17027647http://purl.org/dc/terms/identifier"doi:10.1016/j.bbrc.2006.09.102"xsd:string
http://purl.uniprot.org/citations/17027647http://purl.uniprot.org/core/author"Cho J.-Y."xsd:string
http://purl.uniprot.org/citations/17027647http://purl.uniprot.org/core/author"Cho J.-Y."xsd:string
http://purl.uniprot.org/citations/17027647http://purl.uniprot.org/core/author"Lim J.H."xsd:string
http://purl.uniprot.org/citations/17027647http://purl.uniprot.org/core/author"Lim J.H."xsd:string
http://purl.uniprot.org/citations/17027647http://purl.uniprot.org/core/author"Park Y.B."xsd:string
http://purl.uniprot.org/citations/17027647http://purl.uniprot.org/core/author"Park Y.B."xsd:string
http://purl.uniprot.org/citations/17027647http://purl.uniprot.org/core/author"Park J.-W."xsd:string
http://purl.uniprot.org/citations/17027647http://purl.uniprot.org/core/author"Park J.-W."xsd:string
http://purl.uniprot.org/citations/17027647http://purl.uniprot.org/core/author"Kwon T.K."xsd:string
http://purl.uniprot.org/citations/17027647http://purl.uniprot.org/core/author"Kwon T.K."xsd:string
http://purl.uniprot.org/citations/17027647http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/17027647http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/17027647http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/17027647http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/17027647http://purl.uniprot.org/core/pages"736-741"xsd:string
http://purl.uniprot.org/citations/17027647http://purl.uniprot.org/core/pages"736-741"xsd:string
http://purl.uniprot.org/citations/17027647http://purl.uniprot.org/core/title"ESE-3 transcription factor is involved in the expression of death receptor (DR)-5 through putative Ets sites."xsd:string
http://purl.uniprot.org/citations/17027647http://purl.uniprot.org/core/title"ESE-3 transcription factor is involved in the expression of death receptor (DR)-5 through putative Ets sites."xsd:string
http://purl.uniprot.org/citations/17027647http://purl.uniprot.org/core/volume"350"xsd:string
http://purl.uniprot.org/citations/17027647http://purl.uniprot.org/core/volume"350"xsd:string