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http://purl.uniprot.org/citations/17029201http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17029201http://www.w3.org/2000/01/rdf-schema#comment"

Objective

To analyze the distribution of genes in HLA-Cw locus from Han population of China in a large scale, and to provide basic data for further study on the genetic characteristics of HLA-Cw locus of this population.

Methods

Totally 1285 unrelated Chinese Han individuals were typed by PCR-SSP, and statistics was utilized to investigate the distribution rules of detected genes.

Results

Twenty-three HLA-Cw alleles were identified in Chinese Han population, out of them HLA-Cw*01, *03, *07 and *08 were the commonest genes, which accounted for frequencies of 0.1529, 0.2385, 0.1747 and 0.1004, respectively. Five genes which could not be identified by serological method were deaed: HLA-Cw*12, *14, *15, *16 and *17. Hardy-Weinberg test showed that the observed genetic polymorphism distribution values were correspondent with the expected (chi-square=73.74, df=98, P>0.5).

Conclusion

This study may serve a full-scale scientific genetic parameters of HLA-Cw genes for Chinese Han population studies."xsd:string
http://purl.uniprot.org/citations/17029201http://purl.uniprot.org/core/author"Jin L."xsd:string
http://purl.uniprot.org/citations/17029201http://purl.uniprot.org/core/author"Luo Y."xsd:string
http://purl.uniprot.org/citations/17029201http://purl.uniprot.org/core/author"Liu N."xsd:string
http://purl.uniprot.org/citations/17029201http://purl.uniprot.org/core/author"Yuan F."xsd:string
http://purl.uniprot.org/citations/17029201http://purl.uniprot.org/core/author"Liu J.F."xsd:string
http://purl.uniprot.org/citations/17029201http://purl.uniprot.org/core/author"Liang F."xsd:string
http://purl.uniprot.org/citations/17029201http://purl.uniprot.org/core/author"Liu S.G."xsd:string
http://purl.uniprot.org/citations/17029201http://purl.uniprot.org/core/author"Song X.Q."xsd:string
http://purl.uniprot.org/citations/17029201http://purl.uniprot.org/core/author"Sun Y.Y."xsd:string
http://purl.uniprot.org/citations/17029201http://purl.uniprot.org/core/author"Xi Y.Z."xsd:string
http://purl.uniprot.org/citations/17029201http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/17029201http://purl.uniprot.org/core/name"Zhonghua Yi Xue Yi Chuan Xue Za Zhi"xsd:string
http://purl.uniprot.org/citations/17029201http://purl.uniprot.org/core/pages"528-531"xsd:string
http://purl.uniprot.org/citations/17029201http://purl.uniprot.org/core/title"[Genetic polymorphism of HLA-Cw locus in hematopoietic stem cell transplantation patient and donor population]."xsd:string
http://purl.uniprot.org/citations/17029201http://purl.uniprot.org/core/volume"23"xsd:string
http://purl.uniprot.org/citations/17029201http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/17029201
http://purl.uniprot.org/citations/17029201http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/17029201
http://purl.uniprot.org/uniprot/#_A0A0A7C549-mappedCitation-17029201http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17029201
http://purl.uniprot.org/uniprot/#_A0A0A7C553-mappedCitation-17029201http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17029201
http://purl.uniprot.org/uniprot/#_A0A089N0V0-mappedCitation-17029201http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17029201
http://purl.uniprot.org/uniprot/#_A0A0A7C850-mappedCitation-17029201http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17029201
http://purl.uniprot.org/uniprot/#_A0A0A7C8P1-mappedCitation-17029201http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17029201
http://purl.uniprot.org/uniprot/#_A0A0A7C8P4-mappedCitation-17029201http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17029201