| http://purl.uniprot.org/citations/1703006 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1703006 | http://www.w3.org/2000/01/rdf-schema#comment | "A1 is a major core protein of the mammalian hnRNP complex, and as a purified protein of approximately 34 kDa, A1 is a strong single-stranded nucleic acid binding protein. Several lines of evidence suggest that the protein is organized in discrete domains consisting of an N-terminal segment of approximately 22 kDa and a C-terminal segment of approximately 12 kDa. Each of these domains as a purified fragment is capable of binding to both ssDNA and RNA. We report here that A1 and its C-terminal domain fragment are capable of potent strand-annealing activity for base-pair complementary single-stranded polynucleotides of both RNA and DNA. This effect is not stimulated by ATP. Compared with A1 and the C-terminal fragment, the N-terminal domain fragment has negligible annealing activity. These results indicate that A1 has biochemical activity consistent with a strand-annealing role in relevant reactions, such as pre-mRNA splicing."xsd:string |
| http://purl.uniprot.org/citations/1703006 | http://purl.org/dc/terms/identifier | "doi:10.1021/bi00500a001"xsd:string |
| http://purl.uniprot.org/citations/1703006 | http://purl.uniprot.org/core/author | "Kumar A."xsd:string |
| http://purl.uniprot.org/citations/1703006 | http://purl.uniprot.org/core/author | "Wilson S.H."xsd:string |
| http://purl.uniprot.org/citations/1703006 | http://purl.uniprot.org/core/date | "1990"xsd:gYear |
| http://purl.uniprot.org/citations/1703006 | http://purl.uniprot.org/core/name | "Biochemistry"xsd:string |
| http://purl.uniprot.org/citations/1703006 | http://purl.uniprot.org/core/pages | "10717-10722"xsd:string |
| http://purl.uniprot.org/citations/1703006 | http://purl.uniprot.org/core/title | "Studies of the strand-annealing activity of mammalian hnRNP complex protein A1."xsd:string |
| http://purl.uniprot.org/citations/1703006 | http://purl.uniprot.org/core/volume | "29"xsd:string |
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