http://purl.uniprot.org/citations/1703205 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/1703205 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/1703205 | http://www.w3.org/2000/01/rdf-schema#comment | "In pre-B cells, immunoglobulin mu (Ig mu) is associated with pre-B cell-specific proteins to form a multimeric complex that is found on the cell surface. One of these proteins is encoded by the three exon Ig lambda-like gene 14.1, whose expression is restricted to pre-B cells and occurs from an unrearranged gene. A comparison of the 14.1 gene structure to the seven-gene human Ig lambda locus revealed that the most 5' gene, Ig lambda 1, is organized in a three-exon structure very similar to the 14.1 gene. Transcription and splicing of these three-exon sequences would lead to an mRNA with an open reading frame which could encode a light (L) chain-like protein with a molecular weight of 23,045. Our analysis suggests that two transcripts may be produced from the Ig lambda 1 gene that share the same Ig lambda 1 constant region-containing third exon. One transcript would include all three 14.1-related exons and be expressed from the germline gene, and the second transcript would be produced after variable-joining (V-J) recombination has occurred to Ig lambda J1 and would encode a classic Ig lambda L chain protein. The conservation of the genomic organization of the human 14.1 and Ig lambda 1 genes and the mouse homolog, lambda 5, relative to the classic Ig lambda L chain genes provides insight into the evolution of Ig genes."xsd:string |
http://purl.uniprot.org/citations/1703205 | http://purl.org/dc/terms/identifier | "doi:10.1084/jem.173.2.305"xsd:string |
http://purl.uniprot.org/citations/1703205 | http://purl.org/dc/terms/identifier | "doi:10.1084/jem.173.2.305"xsd:string |
http://purl.uniprot.org/citations/1703205 | http://purl.uniprot.org/core/author | "Hollis G.F."xsd:string |
http://purl.uniprot.org/citations/1703205 | http://purl.uniprot.org/core/author | "Hollis G.F."xsd:string |
http://purl.uniprot.org/citations/1703205 | http://purl.uniprot.org/core/author | "Evans R.J."xsd:string |
http://purl.uniprot.org/citations/1703205 | http://purl.uniprot.org/core/author | "Evans R.J."xsd:string |
http://purl.uniprot.org/citations/1703205 | http://purl.uniprot.org/core/date | "1991"xsd:gYear |
http://purl.uniprot.org/citations/1703205 | http://purl.uniprot.org/core/date | "1991"xsd:gYear |
http://purl.uniprot.org/citations/1703205 | http://purl.uniprot.org/core/name | "J. Exp. Med."xsd:string |
http://purl.uniprot.org/citations/1703205 | http://purl.uniprot.org/core/name | "J. Exp. Med."xsd:string |
http://purl.uniprot.org/citations/1703205 | http://purl.uniprot.org/core/pages | "305-311"xsd:string |
http://purl.uniprot.org/citations/1703205 | http://purl.uniprot.org/core/pages | "305-311"xsd:string |
http://purl.uniprot.org/citations/1703205 | http://purl.uniprot.org/core/title | "Genomic structure of the human Ig lambda 1 gene suggests that it may be expressed as an Ig lambda 14.1-like protein or as a canonical B cell Ig lambda light chain: implications for Ig lambda gene evolution."xsd:string |
http://purl.uniprot.org/citations/1703205 | http://purl.uniprot.org/core/title | "Genomic structure of the human Ig lambda 1 gene suggests that it may be expressed as an Ig lambda 14.1-like protein or as a canonical B cell Ig lambda light chain: implications for Ig lambda gene evolution."xsd:string |
http://purl.uniprot.org/citations/1703205 | http://purl.uniprot.org/core/volume | "173"xsd:string |
http://purl.uniprot.org/citations/1703205 | http://purl.uniprot.org/core/volume | "173"xsd:string |
http://purl.uniprot.org/citations/1703205 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1703205 |
http://purl.uniprot.org/citations/1703205 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1703205 |
http://purl.uniprot.org/citations/1703205 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1703205 |
http://purl.uniprot.org/citations/1703205 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1703205 |
http://purl.uniprot.org/uniprot/P15814 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/1703205 |
http://purl.uniprot.org/uniprot/V9GZI2 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/1703205 |