http://purl.uniprot.org/citations/17032657 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17032657 | http://www.w3.org/2000/01/rdf-schema#comment | "The Dna2 protein is a multifunctional enzyme with 5'-3' DNA helicase, DNA-dependent ATPase, 3' exo/endonuclease, and 5' exo/endonuclease. The enzyme is highly specific for structures containing single-stranded flaps adjacent to duplex regions. We report here two novel activities of both the yeast and human Dna2 helicase/nuclease protein: single strand annealing and ATP-independent strand exchange on short duplexes. These activities are independent of ATPase/helicase and nuclease activities in that mutations eliminating either nuclease or ATPase/helicase do not inhibit strand annealing or strand exchange. ATP inhibits strand exchange. A model rationalizing the multiple catalytic functions of Dna2 and leading to its coordination with other enzymes in processing single-stranded flaps during DNA replication and repair is presented."xsd:string |
http://purl.uniprot.org/citations/17032657 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m604925200"xsd:string |
http://purl.uniprot.org/citations/17032657 | http://purl.uniprot.org/core/author | "Campbell J.L."xsd:string |
http://purl.uniprot.org/citations/17032657 | http://purl.uniprot.org/core/author | "Masuda-Sasa T."xsd:string |
http://purl.uniprot.org/citations/17032657 | http://purl.uniprot.org/core/author | "Polaczek P."xsd:string |
http://purl.uniprot.org/citations/17032657 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
http://purl.uniprot.org/citations/17032657 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
http://purl.uniprot.org/citations/17032657 | http://purl.uniprot.org/core/pages | "38555-38564"xsd:string |
http://purl.uniprot.org/citations/17032657 | http://purl.uniprot.org/core/title | "Single strand annealing and ATP-independent strand exchange activities of yeast and human DNA2: possible role in Okazaki fragment maturation."xsd:string |
http://purl.uniprot.org/citations/17032657 | http://purl.uniprot.org/core/volume | "281"xsd:string |
http://purl.uniprot.org/citations/17032657 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17032657 |
http://purl.uniprot.org/citations/17032657 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17032657 |
http://purl.uniprot.org/uniprot/#_A0A8H4FBD9-mappedCitation-17032657 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17032657 |
http://purl.uniprot.org/uniprot/#_P38859-mappedCitation-17032657 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17032657 |
http://purl.uniprot.org/uniprot/#_P51530-mappedCitation-17032657 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17032657 |
http://purl.uniprot.org/uniprot/A0A8H4FBD9 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17032657 |
http://purl.uniprot.org/uniprot/P38859 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17032657 |
http://purl.uniprot.org/uniprot/P51530 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17032657 |