| http://purl.uniprot.org/citations/17036048 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17036048 | http://www.w3.org/2000/01/rdf-schema#comment | "P2X(7) receptors are ATP-gated cation channels; their activation in macrophage also leads to rapid opening of a membrane pore permeable to dyes such as ethidium, and to release of the pro-inflammatory cytokine, interleukin-1beta (IL-1beta). It has not been known what this dye-uptake path is, or whether it is involved in downstream signalling to IL-1beta release. Here, we identify pannexin-1, a recently described mammalian protein that functions as a hemichannel when ectopically expressed, as this dye-uptake pathway and show that signalling through pannexin-1 is required for processing of caspase-1 and release of mature IL-1beta induced by P2X(7) receptor activation."xsd:string |
| http://purl.uniprot.org/citations/17036048 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.emboj.7601378"xsd:string |
| http://purl.uniprot.org/citations/17036048 | http://purl.uniprot.org/core/author | "Pelegrin P."xsd:string |
| http://purl.uniprot.org/citations/17036048 | http://purl.uniprot.org/core/author | "Surprenant A."xsd:string |
| http://purl.uniprot.org/citations/17036048 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/17036048 | http://purl.uniprot.org/core/name | "EMBO J"xsd:string |
| http://purl.uniprot.org/citations/17036048 | http://purl.uniprot.org/core/pages | "5071-5082"xsd:string |
| http://purl.uniprot.org/citations/17036048 | http://purl.uniprot.org/core/title | "Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor."xsd:string |
| http://purl.uniprot.org/citations/17036048 | http://purl.uniprot.org/core/volume | "25"xsd:string |
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| http://purl.uniprot.org/uniprot/Q96RD7#attribution-C10FA927F3AE341881D3E67C2A562A6F | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/17036048 |
| http://purl.uniprot.org/uniprot/Q99572#attribution-4E1AEB38F1730E7E067214C5236896FA | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/17036048 |
| http://purl.uniprot.org/uniprot/#_A0A0G2KA39-mappedCitation-17036048 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17036048 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JZT0-mappedCitation-17036048 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17036048 |
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| http://purl.uniprot.org/uniprot/#_A6KQJ8-mappedCitation-17036048 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17036048 |
| http://purl.uniprot.org/uniprot/#_A6KQJ9-mappedCitation-17036048 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17036048 |
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| http://purl.uniprot.org/uniprot/#_A0A8I6ARA0-mappedCitation-17036048 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17036048 |