| http://purl.uniprot.org/citations/17056548 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17056548 | http://www.w3.org/2000/01/rdf-schema#comment | "We previously showed that human NK cells used the NKp46 receptor to lyse Mycobacterium tuberculosis H37Ra-infected monocytes. To identify ligands on H37Ra-infected human mononuclear phagocytes, we used anti-NKp46 to immunoprecipitate NKp46 from NK cells bound to its ligand(s) on H37Ra-infected monocytes. Mass spectrometry analysis identified a 57-kDa molecule, vimentin, as a putative ligand for NKp46. Vimentin expression was significantly up-regulated on the surface of infected monocytes, compared with uninfected cells, and this was confirmed by fluorescence microscopy. Anti-vimentin antiserum inhibited NK cell lysis of infected monocytes, whereas antiserum to actin, another filamentous protein, did not. CHO-K1 cells transfected with a vimentin construct were lysed much more efficiently by NK cells than cells transfected with a control plasmid. This lysis was inhibited by mAb-mediated masking of NKp46 (on NK cells) or vimentin (on infected monocytes). ELISA and Far Western blotting showed that recombinant vimentin bound to a NKp46 fusion protein. These results indicate that vimentin is involved in binding of NKp46 to M. tuberculosis H37Ra-infected mononuclear phagocytes."xsd:string |
| http://purl.uniprot.org/citations/17056548 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.177.9.6192"xsd:string |
| http://purl.uniprot.org/citations/17056548 | http://purl.uniprot.org/core/author | "Wu S."xsd:string |
| http://purl.uniprot.org/citations/17056548 | http://purl.uniprot.org/core/author | "Roy S."xsd:string |
| http://purl.uniprot.org/citations/17056548 | http://purl.uniprot.org/core/author | "Garg A."xsd:string |
| http://purl.uniprot.org/citations/17056548 | http://purl.uniprot.org/core/author | "Shetty S."xsd:string |
| http://purl.uniprot.org/citations/17056548 | http://purl.uniprot.org/core/author | "Barnes P.F."xsd:string |
| http://purl.uniprot.org/citations/17056548 | http://purl.uniprot.org/core/author | "Nanda J.S."xsd:string |
| http://purl.uniprot.org/citations/17056548 | http://purl.uniprot.org/core/author | "Porgador A."xsd:string |
| http://purl.uniprot.org/citations/17056548 | http://purl.uniprot.org/core/author | "Rawal N."xsd:string |
| http://purl.uniprot.org/citations/17056548 | http://purl.uniprot.org/core/author | "Griffith D.E."xsd:string |
| http://purl.uniprot.org/citations/17056548 | http://purl.uniprot.org/core/author | "Vankayalapati R."xsd:string |
| http://purl.uniprot.org/citations/17056548 | http://purl.uniprot.org/core/author | "Girard W.M."xsd:string |
| http://purl.uniprot.org/citations/17056548 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/17056548 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
| http://purl.uniprot.org/citations/17056548 | http://purl.uniprot.org/core/pages | "6192-6198"xsd:string |
| http://purl.uniprot.org/citations/17056548 | http://purl.uniprot.org/core/title | "Vimentin expressed on Mycobacterium tuberculosis-infected human monocytes is involved in binding to the NKp46 receptor."xsd:string |
| http://purl.uniprot.org/citations/17056548 | http://purl.uniprot.org/core/volume | "177"xsd:string |
| http://purl.uniprot.org/citations/17056548 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17056548 |
| http://purl.uniprot.org/citations/17056548 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17056548 |
| http://purl.uniprot.org/uniprot/#_A0A0A0MR94-mappedCitation-17056548 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17056548 |
| http://purl.uniprot.org/uniprot/#_A0A0A0MTU0-mappedCitation-17056548 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17056548 |
| http://purl.uniprot.org/uniprot/#_A0A0A0MQZ0-mappedCitation-17056548 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17056548 |
| http://purl.uniprot.org/uniprot/#_A0A0S2Z4T0-mappedCitation-17056548 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17056548 |