| http://purl.uniprot.org/citations/17072319 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17072319 | http://www.w3.org/2000/01/rdf-schema#comment | "CD23, the low-affinity immunoglobulin E receptor, is an important modulator of the allergic response and of diseases such as rheumatoid arthritis. The proteolytic release of CD23 from cells is considered a key event in the allergic response. Here we used loss-of-function and gain-of-function experiments with cells lacking or overexpressing candidate CD23-releasing enzymes (ADAM8, ADAM9, ADAM10, ADAM12, ADAM15, ADAM17, ADAM19 and ADAM33), ADAM-knockout mice and a selective inhibitor to identify ADAM10 as the main CD23-releasing enzyme in vivo. Our findings provide a likely target for the treatment of allergic reactions and set the stage for further studies of the involvement of ADAM10 in CD23-dependent pathologies."xsd:string |
| http://purl.uniprot.org/citations/17072319 | http://purl.org/dc/terms/identifier | "doi:10.1038/ni1399"xsd:string |
| http://purl.uniprot.org/citations/17072319 | http://purl.uniprot.org/core/author | "Martin S."xsd:string |
| http://purl.uniprot.org/citations/17072319 | http://purl.uniprot.org/core/author | "Saftig P."xsd:string |
| http://purl.uniprot.org/citations/17072319 | http://purl.uniprot.org/core/author | "Swendeman S."xsd:string |
| http://purl.uniprot.org/citations/17072319 | http://purl.uniprot.org/core/author | "Becherer J.D."xsd:string |
| http://purl.uniprot.org/citations/17072319 | http://purl.uniprot.org/core/author | "Black R.A."xsd:string |
| http://purl.uniprot.org/citations/17072319 | http://purl.uniprot.org/core/author | "Blobel C.P."xsd:string |
| http://purl.uniprot.org/citations/17072319 | http://purl.uniprot.org/core/author | "Docherty A.J."xsd:string |
| http://purl.uniprot.org/citations/17072319 | http://purl.uniprot.org/core/author | "Hartmann D."xsd:string |
| http://purl.uniprot.org/citations/17072319 | http://purl.uniprot.org/core/author | "Weskamp G."xsd:string |
| http://purl.uniprot.org/citations/17072319 | http://purl.uniprot.org/core/author | "Ludwig A."xsd:string |
| http://purl.uniprot.org/citations/17072319 | http://purl.uniprot.org/core/author | "Conrad D.H."xsd:string |
| http://purl.uniprot.org/citations/17072319 | http://purl.uniprot.org/core/author | "Umland S."xsd:string |
| http://purl.uniprot.org/citations/17072319 | http://purl.uniprot.org/core/author | "Sehara-Fujisawa A."xsd:string |
| http://purl.uniprot.org/citations/17072319 | http://purl.uniprot.org/core/author | "Ford J.W."xsd:string |
| http://purl.uniprot.org/citations/17072319 | http://purl.uniprot.org/core/author | "Broadway N."xsd:string |
| http://purl.uniprot.org/citations/17072319 | http://purl.uniprot.org/core/author | "Sturgill J."xsd:string |
| http://purl.uniprot.org/citations/17072319 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/17072319 | http://purl.uniprot.org/core/name | "Nat Immunol"xsd:string |
| http://purl.uniprot.org/citations/17072319 | http://purl.uniprot.org/core/pages | "1293-1298"xsd:string |
| http://purl.uniprot.org/citations/17072319 | http://purl.uniprot.org/core/title | "ADAM10 is a principal 'sheddase' of the low-affinity immunoglobulin E receptor CD23."xsd:string |
| http://purl.uniprot.org/citations/17072319 | http://purl.uniprot.org/core/volume | "7"xsd:string |
| http://purl.uniprot.org/citations/17072319 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17072319 |