http://purl.uniprot.org/citations/17082457 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17082457 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17082457 | http://www.w3.org/2000/01/rdf-schema#comment | "Guanosine triphosphatases of the Rab family are key regulators of membrane trafficking, with Rab11 playing a specific role in membrane recycling. We identified a mammalian protein, protrudin, that promoted neurite formation through interaction with the guanosine diphosphate (GDP)-bound form of Rab11. Phosphorylation of protrudin by extracellular signal-regulated kinase (ERK) in response to nerve growth factor promoted protrudin association with Rab11-GDP. Down-regulation of protrudin by RNA interference induced membrane extension in all directions and inhibited neurite formation. Thus, protrudin regulates Rab11-dependent membrane recycling to promote the directional membrane trafficking required for neurite formation."xsd:string |
http://purl.uniprot.org/citations/17082457 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1134027"xsd:string |
http://purl.uniprot.org/citations/17082457 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1134027"xsd:string |
http://purl.uniprot.org/citations/17082457 | http://purl.uniprot.org/core/author | "Nakayama K.I."xsd:string |
http://purl.uniprot.org/citations/17082457 | http://purl.uniprot.org/core/author | "Nakayama K.I."xsd:string |
http://purl.uniprot.org/citations/17082457 | http://purl.uniprot.org/core/author | "Shirane M."xsd:string |
http://purl.uniprot.org/citations/17082457 | http://purl.uniprot.org/core/author | "Shirane M."xsd:string |
http://purl.uniprot.org/citations/17082457 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
http://purl.uniprot.org/citations/17082457 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
http://purl.uniprot.org/citations/17082457 | http://purl.uniprot.org/core/name | "Science"xsd:string |
http://purl.uniprot.org/citations/17082457 | http://purl.uniprot.org/core/name | "Science"xsd:string |
http://purl.uniprot.org/citations/17082457 | http://purl.uniprot.org/core/pages | "818-821"xsd:string |
http://purl.uniprot.org/citations/17082457 | http://purl.uniprot.org/core/pages | "818-821"xsd:string |
http://purl.uniprot.org/citations/17082457 | http://purl.uniprot.org/core/title | "Protrudin induces neurite formation by directional membrane trafficking."xsd:string |
http://purl.uniprot.org/citations/17082457 | http://purl.uniprot.org/core/title | "Protrudin induces neurite formation by directional membrane trafficking."xsd:string |
http://purl.uniprot.org/citations/17082457 | http://purl.uniprot.org/core/volume | "314"xsd:string |
http://purl.uniprot.org/citations/17082457 | http://purl.uniprot.org/core/volume | "314"xsd:string |
http://purl.uniprot.org/citations/17082457 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17082457 |
http://purl.uniprot.org/citations/17082457 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17082457 |
http://purl.uniprot.org/citations/17082457 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17082457 |
http://purl.uniprot.org/citations/17082457 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17082457 |
http://purl.uniprot.org/uniprot/P62491 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/17082457 |
http://purl.uniprot.org/uniprot/P62494 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/17082457 |