| http://purl.uniprot.org/citations/17086444 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17086444 | http://www.w3.org/2000/01/rdf-schema#comment | "SURF-6 is a bona fide nucleolar protein comprising an evolutionary conserved family that extends from human to yeast. The expression of the mammalian SURF-6 has been recently found to be regulated during the cell cycle. In order to determine the importance of SURF-6 in mammalian cells, we applied the Tet-On system to regulate conditionally, in response to tetracycline, the expression of an antisense RNA (asRNA) that targets Surf-6 mRNA in mouse NIH/3T3 cells. Induced Surf-6 asRNA caused an effective depletion of SURF-6 protein resulted in cell death and in an apparent arrest in the G1 phase of the cell cycle. These results provide for the first time evidence that expression of SURF-6 is essential for mammalian cell viability, and suggest that SURF-6 might participate in the progression of cell cycle."xsd:string |
| http://purl.uniprot.org/citations/17086444 | http://purl.org/dc/terms/identifier | "doi:10.1007/s11033-006-9028-4"xsd:string |
| http://purl.uniprot.org/citations/17086444 | http://purl.uniprot.org/core/author | "Zatsepina O."xsd:string |
| http://purl.uniprot.org/citations/17086444 | http://purl.uniprot.org/core/author | "Magoulas C."xsd:string |
| http://purl.uniprot.org/citations/17086444 | http://purl.uniprot.org/core/author | "Polzikov M."xsd:string |
| http://purl.uniprot.org/citations/17086444 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17086444 | http://purl.uniprot.org/core/name | "Mol Biol Rep"xsd:string |
| http://purl.uniprot.org/citations/17086444 | http://purl.uniprot.org/core/pages | "155-160"xsd:string |
| http://purl.uniprot.org/citations/17086444 | http://purl.uniprot.org/core/title | "The nucleolar protein SURF-6 is essential for viability in mouse NIH/3T3 cells."xsd:string |
| http://purl.uniprot.org/citations/17086444 | http://purl.uniprot.org/core/volume | "34"xsd:string |
| http://purl.uniprot.org/citations/17086444 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17086444 |
| http://purl.uniprot.org/citations/17086444 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17086444 |
| http://purl.uniprot.org/uniprot/#_Q3V1X4-mappedCitation-17086444 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17086444 |
| http://purl.uniprot.org/uniprot/#_P70279-mappedCitation-17086444 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17086444 |
| http://purl.uniprot.org/uniprot/P70279 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17086444 |
| http://purl.uniprot.org/uniprot/Q3V1X4 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17086444 |