| http://purl.uniprot.org/citations/1709048 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1709048 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1709048 | http://www.w3.org/2000/01/rdf-schema#comment | "The human haemopoietic cell surface antigen, CD34, is a 105 - 120 kd cell surface glycoprotein whose stage-specific expression by stem cells and lineage-specific progenitor cells suggests a role in regulating early events in blood cell differentiation. A murine gene and cDNA encoding a closely homologous protein have been isolated. The gene is organized in eight exons in 22 kb of DNA. The first exon lies in a GC- and CpG-rich island. The sequence of the gene and the cDNA predict a 382 amino acid-long protein containing an N-terminal signal peptide and one transmembrane region 73 amino acids from the C-terminus. The extracellular part of the protein contains: a 140 amino acid-long-N-terminal region, 40% of whose residues are serine or threonine potential attachment sites for O-linked carbohydrate, as well as five potential attachment sites for N-linked carbohydrate. Proximal to the extracellular membrane there is a 79 amino acid-long cysteine-rich region. The homology with the human sequence is highest in the intracellular domain (90% amino acid identity) and lowest in the N-terminal region (43% amino acid identity). The protein is not homologous with any other proteins currently in the databases. The expression of the murine gene by a number of haemopoietic progenitor cell lines suggests that the CD34 function in haemopoiesis may be conserved between man and mouse. The high level of expression in a number of embryonic fibroblast cell lines and in brain imply a function outside of haemopoiesis."xsd:string |
| http://purl.uniprot.org/citations/1709048 | http://purl.org/dc/terms/identifier | "doi:10.1093/intimm/3.2.175"xsd:string |
| http://purl.uniprot.org/citations/1709048 | http://purl.org/dc/terms/identifier | "doi:10.1093/intimm/3.2.175"xsd:string |
| http://purl.uniprot.org/citations/1709048 | http://purl.uniprot.org/core/author | "Brown J."xsd:string |
| http://purl.uniprot.org/citations/1709048 | http://purl.uniprot.org/core/author | "Brown J."xsd:string |
| http://purl.uniprot.org/citations/1709048 | http://purl.uniprot.org/core/author | "Greaves M.F."xsd:string |
| http://purl.uniprot.org/citations/1709048 | http://purl.uniprot.org/core/author | "Greaves M.F."xsd:string |
| http://purl.uniprot.org/citations/1709048 | http://purl.uniprot.org/core/author | "Molgaard H.V."xsd:string |
| http://purl.uniprot.org/citations/1709048 | http://purl.uniprot.org/core/author | "Molgaard H.V."xsd:string |
| http://purl.uniprot.org/citations/1709048 | http://purl.uniprot.org/core/date | "1991"xsd:gYear |
| http://purl.uniprot.org/citations/1709048 | http://purl.uniprot.org/core/date | "1991"xsd:gYear |
| http://purl.uniprot.org/citations/1709048 | http://purl.uniprot.org/core/name | "Int. Immunol."xsd:string |
| http://purl.uniprot.org/citations/1709048 | http://purl.uniprot.org/core/name | "Int. Immunol."xsd:string |
| http://purl.uniprot.org/citations/1709048 | http://purl.uniprot.org/core/pages | "175-184"xsd:string |
| http://purl.uniprot.org/citations/1709048 | http://purl.uniprot.org/core/pages | "175-184"xsd:string |
| http://purl.uniprot.org/citations/1709048 | http://purl.uniprot.org/core/title | "The gene encoding the stem cell antigen, CD34, is conserved in mouse and expressed in haemopoietic progenitor cell lines, brain, and embryonic fibroblasts."xsd:string |
| http://purl.uniprot.org/citations/1709048 | http://purl.uniprot.org/core/title | "The gene encoding the stem cell antigen, CD34, is conserved in mouse and expressed in haemopoietic progenitor cell lines, brain, and embryonic fibroblasts."xsd:string |
| http://purl.uniprot.org/citations/1709048 | http://purl.uniprot.org/core/volume | "3"xsd:string |
| http://purl.uniprot.org/citations/1709048 | http://purl.uniprot.org/core/volume | "3"xsd:string |
| http://purl.uniprot.org/citations/1709048 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1709048 |
| http://purl.uniprot.org/citations/1709048 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1709048 |
| http://purl.uniprot.org/citations/1709048 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1709048 |
| http://purl.uniprot.org/citations/1709048 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1709048 |